| Gene Symbol |
B3GNT2
|
| Entrez Gene |
10678
|
| Alt Symbol |
B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
|
| Other Description |
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2|UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1|beta-1,3-Gn-T1|beta-1,3-Gn-T2|beta-1,3-N-acetylglucosaminyltransferase bGnT-1|beta-1,3-N-acetylglucosaminyltransferase bGnT-2|beta3Gn-T1|beta3Gn-T2
|
| Swissprots |
Q9NY97 Q9NQQ9 Q54AC1 Q9NQR0 Q9NUT9
|
| Accessions |
AAX93271 EAW99977 EAW99978 EAW99979 EAW99980 Q9NY97 AB049584 BAB21530 AF092051 AAD09764 AF288208 AAF97253 AF288209 AAF97254 AJ006077 CAB91546 AK002009 BAA92031 BC030579 AAH30579 BC047933 AAH47933 HQ447202 ADQ31689 XM_011532486 XP_011530788 NM_006577 NP_006568 NM_033252
|
| Function |
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase. {ECO:0000269|PubMed:11042166, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:9892646}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:11042166}.
|
| Top Pathways |
Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series
|
![Western Blot: B3GNT2 Overexpression Lysate (Adult Normal) [NBL1-07884] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for B3GNT2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7843_B3GNT2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07884-img0002.jpg)