Gene Symbol | B3GNT2 |
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Entrez Gene | 10678 |
Alt Symbol | B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
Other Description | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2|UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1|beta-1,3-Gn-T1|beta-1,3-Gn-T2|beta-1,3-N-acetylglucosaminyltransferase bGnT-1|beta-1,3-N-acetylglucosaminyltransferase bGnT-2|beta3Gn-T1|beta3Gn-T2 |
Swissprots | Q9NY97 Q9NQQ9 Q54AC1 Q9NQR0 Q9NUT9 |
Accessions | AAX93271 EAW99977 EAW99978 EAW99979 EAW99980 Q9NY97 AB049584 BAB21530 AF092051 AAD09764 AF288208 AAF97253 AF288209 AAF97254 AJ006077 CAB91546 AK002009 BAA92031 BC030579 AAH30579 BC047933 AAH47933 HQ447202 ADQ31689 XM_011532486 XP_011530788 NM_006577 NP_006568 NM_033252 |
Function | Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase. {ECO:0000269|PubMed:11042166, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:9892646}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11042166}. |
Top Pathways | Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series |
Human B3GNT1 full length protein - ab161107 from Abcam
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Human B3GNT1 protein fragment - ab161108 from Abcam
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B3GNT2 Antibody Blocking Peptide - LS-E26468 from LifeSpan Bioscience
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Recombinant Protein - H00010678-P01 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Partial Recombinant Protein - H00010678-Q01 from Novus Biologicals
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Recombinant Human B3GNT2, CF - 3960-GT-020 from R&D Systems
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Human B3GNT2 protein - orb138226 from Biorbyt
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B3GNT1 Peptide - AC21-1306-P from Abcore
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B3GNT2 / B3GALT7 - H00010678-P01-10 from Acris Antibodies
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B3GNT2 / B3GALT7 - H00010678-P01-25 from Acris Antibodies
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B3GNT2 / B3GALT7 - H00010678-Q01-10 from Acris Antibodies
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B3GNT2 / B3GALT7 - H00010678-Q01-25 from Acris Antibodies
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B3GNT2 Peptide - 46-631P from ProSci
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B3GNT2 fusion protein - Ag5404 from Proteintech Group
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Recombinant Human B3GNT2, Fc tagged - B3GNT2-8546H from Creative Biomart
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Recombinant Human B3GNT2, His-tagged - B3GNT2-10103H from Creative Biomart
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Human B3GNT2 Protein (Fc Tag) - 11416-H01H-20 from Sino Biological
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Recombinant Human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2(B3GNT2) - CSB-YP002500HU CSB-EP002500HU CSB-BP002500HU CSB-MP002500HU from Cusabio
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Recombinant Human B3GNT2 Protein, CF - 3960-GT from R&D Systems
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B3GNT2 / B3GALT7 - TP308100 from Acris Antibodies
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B3GNT2 / B3GALT7 - H00010678-P01 from Acris Antibodies
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B3GNT2, Peptide - MBS426227 from MyBioSource
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Recombinant Human B3GNT2 Protein (Fc tag) - PKSH031125 from Elabscience
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Recombinant Protein Antigen - NBP1-88951PEP from Novus Biologicals
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B3GNT2 Peptide, Human - M34GP01267H from Creative Peptides
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