Gene Symbol | RAB3GAP1 |
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Entrez Gene | 22930 |
Alt Symbol | P130, RAB3GAP, RAB3GAP130, WARBM1 |
Species | Human |
Gene Type | protein-coding |
Description | RAB3 GTPase activating protein subunit 1 (catalytic) |
Other Description | RAB3 GTPase-activating protein 130 kDa subunit|rab3 GTPase-activating protein catalytic subunit|rab3-GAP p130 |
Swissprots | Q15042 A6H8Z3 Q8TBB4 Q659F5 C9J837 |
Accessions | EAX11637 EAX11638 EAX11639 EAX11640 EAX11641 Q15042 AB449877 BAH16620 AK022494 AK056058 AK309118 AL096752 CAH56411 BC020303 BC022977 AAH22977 BC030992 BC036732 BC071602 BC146809 AAI46810 BP872264 D31886 BAA06684 DA333844 XM_011510822 XP_011509124 XM_011510823 XP_011509125 XM_011510824 XP_011509126 XM_011510825 XP_011509127 NM_001172435 NP_001165906 NM_012233 NP_036365 |
Function | Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. {ECO:0000269|PubMed:10859313, ECO:0000269|PubMed:9030515}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9852129}. Note=In neurons, it is enriched in the synaptic soluble fraction. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9030515}. |
RAB3GAP1 peptide - orb218418 from Biorbyt
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RAB3GAP1 Blocking Peptide - abx063749 from Abbexa
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RAB3GAP1 fusion protein - Ag16426 from Proteintech Group
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RAB3GAP1 fusion protein - Ag17710 from Proteintech Group
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Recombinant Human RAB3GAP1, GST-tagged - RAB3GAP1-2122H from Creative Biomart
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RAB3GAP1 Blocking Peptide - CBP2555 from Cohesion Biosciences
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RAB3GAP1 Peptide - BS5874P from Bioworld Technology
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Recombinant Human Rab3 GTPase-activating protein catalytic subunit(RAB3GAP1) ,partial - CSB-YP621861HU CSB-EP621861HU CSB-BP621861HU CSB-MP621861HU from Cusabio
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RAB3GAP1 / RAB3GAP (transcript variant 1) - TP330602 from Acris Antibodies
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RAB3GAP1 Protein - NBP1-83051PEP from Novus Biologicals
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RAB3GAP1 Recombinant Protein Antigen - NBP2-38206PEP from Novus Biologicals
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RAB3GAP1-Antibody-Center-Blocking-peptide - BP10389c from Abgent, a WuXi AppTec company
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RAB3GAP1 Peptide, Human - M34GP12858H from Creative Peptides
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Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1), partial, Recombinant Protein - MBS1399852 from MyBioSource
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Recombinant Human RAB3GAP1 Protein, MYC/DDK-tagged - RAB3GAP1-304H from Creative Biomart
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