| Gene Symbol | THOP1 |
|---|---|
| Entrez Gene | 7064 |
| Alt Symbol | EP24.15, MEPD_HUMAN, MP78, TOP |
| Species | Human |
| Gene Type | protein-coding |
| Description | thimet oligopeptidase 1 |
| Other Description | endopeptidase 24.15|thimet oligopeptidase |
| Swissprots | B3KSE2 P52888 Q9UCB3 |
| Accessions | AAA82606 AAD13118 CBG17384 CBV30826 EAW69364 EAW69365 P52888 AK093392 BAG52704 AK300552 BAG62258 BC000135 AAH00135 BC000583 AAH00583 BC002391 AAH02391 BC013878 AAH13878 BC067281 EU176234 ABW03685 U29366 AAA82607 Z50115 CAA90477 XM_011528228 XP_011526530 NM_003249 NP_003240 |
| Function | Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | African trypanosomiasis, Renin-angiotensin system |