| Gene Symbol |
THOP1
|
| Entrez Gene |
7064
|
| Alt Symbol |
EP24.15, MEPD_HUMAN, MP78, TOP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thimet oligopeptidase 1
|
| Other Description |
endopeptidase 24.15|thimet oligopeptidase
|
| Swissprots |
B3KSE2 P52888 Q9UCB3
|
| Accessions |
AAA82606 AAD13118 CBG17384 CBV30826 EAW69364 EAW69365 P52888 AK093392 BAG52704 AK300552 BAG62258 BC000135 AAH00135 BC000583 AAH00583 BC002391 AAH02391 BC013878 AAH13878 BC067281 EU176234 ABW03685 U29366 AAA82607 Z50115 CAA90477 XM_011528228 XP_011526530 NM_003249 NP_003240
|
| Function |
Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
African trypanosomiasis, Renin-angiotensin system
|
![Western Blot: Thimet Oligopeptidase Overexpression Lysate (Adult Normal) [NBL1-16893] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Thimet Oligopeptidase.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8951_Thimet%2520Oligopeptidase%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-16893-img0002.jpg)