Gene Symbol | THOP1 |
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Entrez Gene | 7064 |
Alt Symbol | EP24.15, MEPD_HUMAN, MP78, TOP |
Species | Human |
Gene Type | protein-coding |
Description | thimet oligopeptidase 1 |
Other Description | endopeptidase 24.15|thimet oligopeptidase |
Swissprots | B3KSE2 P52888 Q9UCB3 |
Accessions | AAA82606 AAD13118 CBG17384 CBV30826 EAW69364 EAW69365 P52888 AK093392 BAG52704 AK300552 BAG62258 BC000135 AAH00135 BC000583 AAH00583 BC002391 AAH02391 BC013878 AAH13878 BC067281 EU176234 ABW03685 U29366 AAA82607 Z50115 CAA90477 XM_011528228 XP_011526530 NM_003249 NP_003240 |
Function | Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. |
Subcellular Location | Cytoplasm. |
Top Pathways | African trypanosomiasis, Renin-angiotensin system |
Thimet oligopeptidase (IVD6) Mouse mAb - 4238 from Cell Signaling Technology
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Thimet oligopeptidase (D-10) - sc-377153 from Santa Cruz Biotechnology
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Thimet oligopeptidase (H-52) - sc-292630 from Santa Cruz Biotechnology
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Thimet oligopeptidase (4D6) - sc-53565 from Santa Cruz Biotechnology
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Thimet oligopeptidase (E-17) - sc-30579 from Santa Cruz Biotechnology
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Thimet oligopeptidase (Q-17) - sc-30578 from Santa Cruz Biotechnology
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Anti-Thimet Oligopeptidase antibody - ab59484 from Abcam
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Anti-Thimet Oligopeptidase antibody - ab59486 from Abcam
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Anti-Thimet Oligopeptidase antibody - ab59490 from Abcam
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Anti-Thimet Oligopeptidase antibody [2D3] - ab119002 from Abcam
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Anti-Thimet Oligopeptidase antibody [EPR7651] - ab154173 from Abcam
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Anti-Thimet Oligopeptidase antibody [IVD6] - ab50626 from Abcam
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Anti-Thimet Oligopeptidase antibody - Catalytic domain - ab59487 from Abcam
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa1-689) - LS-C39599 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72) - LS-C92739 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody - LS-C76364 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72, clone 4D6, Biotin) - LS-C142206 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72, clone 4D6, DY650) - LS-C142207 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72, clone 4D6, DY488) - LS-C142208 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72, clone 4D6, HRP) - LS-C142209 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (clone 2B4) - LS-C198341 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa56-72, clone 4D6, DY550) - LS-C142210 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (aa451-597) - LS-C314998 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (C-Terminus) - LS-C169932 from LifeSpan Bioscience
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Anti-THOP1 / Thimet Oligopeptidase Antibody (clone 2D3) - LS-C115398 from LifeSpan Bioscience
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