SFN

Gene Symbol SFN
Entrez Gene 2810
Alt Symbol YWHAS
Species Human
Gene Type protein-coding
Description stratifin
Other Description 14-3-3 protein sigma|14-3-3 sigma|epithelial cell marker protein 1
Swissprots Q6FH51 Q96DH0 P31947 Q6FH30
Accessions AAC52029 EAX07786 EAX07787 P31947 AF029082 AAC52030 BC000329 AAH00329 BC000995 AAH00995 BC001550 AAH01550 BC002995 AAH02995 BC023552 AAH23552 CR541905 CAG46703 CR541926 CAG46724 DQ894162 ABM85088 M93010 AAA59546 NM_006142 NP_006133
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. {ECO:0000269|PubMed:18382127}.
Subcellular Location Cytoplasm. Nucleus {ECO:0000250}. Secreted. Note=May be secreted by a non-classical secretory pathway.
Tissue Specificity Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
Top Pathways Cell cycle, p53 signaling pathway, Aldosterone-regulated sodium reabsorption

Human SFN / Stratifin / 14-3-3 Sigma ELISA Kit (Sandwich ELISA) - LS-F6557 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 31.25 pg/ml
Range 31.25-2000 pg/ml

Rabbit anti-14-3-3 Sigma Antibody, Affinity Purified - PLA0201 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunohistochemistry</B><BR/>Rabbit Anti-14-3-3 Sigma Antibody, Affinity Purified: <B>Cat. No. PLA0201</B>: Detection of Human 14-3-3 Sigma by Immunohistochemistry. Sample: FFPE section of Human ovarian carcinoma. Antibody: Affinity purified Rabbit Anti-14-3-3 Sigma (<B>Cat. No. PLA0201</B>) used at a dilution of 1:1,000 (1 μg/mL). Detection: DAB

Stratifin (SFN), Human, ELISA Kit - SEH179Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.134ng/mL
Range 0.312-20ng/mL

SFN (Human) IP-WB Antibody Pair - H00002810-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

Strabismus (STBM), ELISA Kit - MBS9311431 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

stratifin, ELISA Kit - MBS909837 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human SFN is typically less than 0.195 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 0.78 ng/ml -50 ng/ml.

Stratifin, ELISA Kit - MBS083504 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS052810 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS087891 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS086421 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS072370 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS093651 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin, ELISA Kit - MBS066549 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 10pg/ml.
Range 62.5pg/ml-2000pg/ml.

StRatifin (SFN), ELISA Kit - MBS9314086 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Stratifin (SFN), ELISA Kit - MBS2020685 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 13.5pg/mL.
Range 31.25-2000pg/mL

14 3 3 protein sigma, ELISA Kit - MBS7225860 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7246862 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7203857 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7201328 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7239985 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7221076 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7221094 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7242176 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7211725 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

14-3-3 protein sigma (SFN), ELISA Kit - MBS7226585 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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