| Gene Symbol |
MARK3
|
| Entrez Gene |
4140
|
| Alt Symbol |
CTAK1, KP78, PAR1A, Par-1a
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAP/microtubule affinity-regulating kinase 3
|
| Other Description |
C-TAK1|ELKL motif kinase 2|EMK-2|cdc25C-associated protein kinase 1|protein kinase STK10|ser/Thr protein kinase PAR-1|serine/threonine-protein kinase p78
|
| Swissprots |
Q9UN34 Q9UMY9 Q8TB41 Q96RG1 Q8WX83 P27448 O60219 Q86TT8
|
| Accessions |
EAW81812 EAW81813 EAW81814 EAW81815 EAW81816 EAW81817 EAW81818 EAW81819 P27448 AB209542 BAD92779 AF170723 AAD51631 AF387637 AAK82367 AF465413 AAL69982 AK055814 AK124459 AK296643 BAG59243 AK307448 BC024773 AAH24773 BX161395 CAD61882 BX248250 CAD62578 DA707357 DQ368336 ABD15137 DQ891715 ABM82641 DQ894892 ABM85818 M80359 AAA59991 M83780 U64205 AAC15093 XM_005267641 XP_005267698 XM_005267642 XP_005267699 XM_005267643 XP_005267700 XM_006720146 XP_006720209 XM_011536768 XP_011535070 XM_011536769 XP_011535071 XM_011536770 XP_011535072 XM_011536771 XP_011535073 NM_001128918 NP_001122390 NM_001128919 NP_001122391 NM_001128920 NP_001122392 NM_001128921 NP_001122393 NM_002376 NP_002367
|
| Function |
Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. {ECO:0000269|PubMed:16980613}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:21145462}; Peripheral membrane protein {ECO:0000269|PubMed:21145462}.
|
| Tissue Specificity |
Ubiquitous.
|