MARK3

Gene Symbol	MARK3
Entrez Gene	4140
Alt Symbol	CTAK1, KP78, PAR1A, Par-1a
Species	Human
Gene Type	protein-coding
Description	MAP/microtubule affinity-regulating kinase 3
Other Description	C-TAK1|ELKL motif kinase 2|EMK-2|cdc25C-associated protein kinase 1|protein kinase STK10|ser/Thr protein kinase PAR-1|serine/threonine-protein kinase p78
Swissprots	Q9UN34 Q9UMY9 Q8TB41 Q96RG1 Q8WX83 P27448 O60219 Q86TT8
Accessions	EAW81812 EAW81813 EAW81814 EAW81815 EAW81816 EAW81817 EAW81818 EAW81819 P27448 AB209542 BAD92779 AF170723 AAD51631 AF387637 AAK82367 AF465413 AAL69982 AK055814 AK124459 AK296643 BAG59243 AK307448 BC024773 AAH24773 BX161395 CAD61882 BX248250 CAD62578 DA707357 DQ368336 ABD15137 DQ891715 ABM82641 DQ894892 ABM85818 M80359 AAA59991 M83780 U64205 AAC15093 XM_005267641 XP_005267698 XM_005267642 XP_005267699 XM_005267643 XP_005267700 XM_006720146 XP_006720209 XM_011536768 XP_011535070 XM_011536769 XP_011535071 XM_011536770 XP_011535072 XM_011536771 XP_011535073 NM_001128918 NP_001122390 NM_001128919 NP_001122391 NM_001128920 NP_001122392 NM_001128921 NP_001122393 NM_002376 NP_002367
Function	Involved in the specific phosphorylation of microtubule- associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. {ECO:0000269|PubMed:16980613}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:21145462}; Peripheral membrane protein {ECO:0000269|PubMed:21145462}.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Mark3 full length protein - ab60012 from Abcam Category Protein Prices $302.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human Mark3 full length protein - ab158858 from Abcam Category Protein Source Wheat germ Species Human

Human Mark3 protein fragment - ab158859 from Abcam Category Protein Source Wheat germ Species Human

Human Mark3 protein fragment - ab158860 from Abcam Category Protein Source Wheat germ Species Human

C-TAK1 / MARK3 Antibody Blocking Peptide - LS-E3130 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

C-TAK1 / MARK3 Antibody Blocking Peptide - LS-E20438 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Mark3 Partial Recombinant Protein - H00004140-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Mark3 Protein - H00004140-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Mark3 Protein - H00004140-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Mark3 Recombinant Protein - P4720 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

Human C-TAK1 protein - orb84423 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 20 μg, 50 μg Source Insect Species Human

MARK3 Blocking Peptide - 33R-1579 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MARK3 - H00004140-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MARK3 - H00004140-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MARK3 - H00004140-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MARK3 - H00004140-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MARK3 - H00004140-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

MARK3 - H00004140-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MARK3 - H00004140-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MARK3 - P4720 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

MARK3 - P5727 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

CTAK1 fusion protein - Ag3805 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CTAK1 fusion protein - Ag8303 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CTAK1, GST-tagged - CTAK1-11658H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human MARK3, GST-tagged, Active - MARK3-349H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus.

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