NFKB2

Gene Symbol NFKB2
Entrez Gene 4791
Alt Symbol CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p52
Species Human
Gene Type protein-coding
Description nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Other Description DNA-binding factor KBF2|NFKB, p52/p100 subunit|lymphocyte translocation chromosome 10 protein|nuclear factor Kappa-B, subunit 2|nuclear factor NF-kappa-B p100 subunit|nuclear factor NF-kappa-B p52 subunit|nuclear factor of Kappa light chain gene enhancer in B cells 2|oncogene Lyt-10|transcription factor NFKB2
Swissprots Q04860 D3DR83 Q00653 Q9H471 A8K9D9 Q9H472 Q9BU75
Accessions AAA68171 AAB23437 AAW56071 CAA58721 CBX47422 CBX47423 CBX47424 EAW49700 EAW49701 EAW49702 EAW49703 EAW49704 EAW49705 EAW49706 Q00653 AK098415 AK292654 BAF85343 BC002844 AAH02844 BT009769 AAP88771 BY799958 DA349980 DA408461 DA711063 DB091090 S76638 AAB21124 U09609 AAA21462 X61498 CAA43715 X61499 CAA43716 XM_005269860 XP_005269917 XM_005269861 XP_005269918 XM_011539830 XP_011538132 XM_011539831 XP_011538133 NM_001077494 NP_001070962 NM_001261403 NP_001248332 NM_001288724 NP_001275653 NM_002502 NP_002493
Function NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cy
Subcellular Location Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Top Pathways MAPK signaling pathway, Osteoclast differentiation, HTLV-I infection, Legionellosis, Viral carcinogenesis

Human NFkB p100 / p52 full length protein - ab125611 from Abcam

Category Protein
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of ab125611.

NFkB p100 / p52 peptide - ab8007 from Abcam

Category Peptide

NFKB2 Antibody Blocking Peptide - LS-E11502 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NFkB p100/p52 Blocking Peptide - NBP2-22372PEP from Novus Biologicals

Category Peptide
Prices $169.00
Sizes 0.05 µg
Species Human

Human NFkB2 Protein - abx068341 from Abbexa

Category Protein
Source E.coli
Species Human

NFKB2 / NF-kappa-B p100/p52 control peptide - R1011CP from Acris Antibodies

Category Peptide
Prices $109.00
Sizes 50 µg

Nuclear Factor Kappa B2 (NFkB2), Human - 20-8060 from ARP American Research Products

Category Protein
Prices $419.00
Sizes 50 µg
Source E.coli
Species Human

NFKB2 fusion protein - Ag0662 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

NFkappaB-p100/p52 (Phospho-Ser865) Antibody Blocking Peptide - GWB-7F5A8C from Genway Biotech

Category Peptide
Prices $138.00
Sizes 100 µg

NFkappaB-p100/p52 (Ser869) Antibody Blocking Peptide - GWB-DA39B0 from Genway Biotech

Category Peptide
Prices $138.00
Sizes 100 µg

Recombinant Human NFKB2, GST-tagged - NFKB2-7052H from Creative Biomart

Category Protein
Source Sf9 Cells
Species Human

Recombinant Human NFKB2, GST-tagged - NFKB2-4859H from Creative Biomart

Category Protein
Source Sf9 insect cells
Species Human

Recombinant Human NFKB2, GST-tagged - NFKB2-1280H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Nuclear Factor Kappa B2 (NFkB2) - RPB825Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Nuclear Factor Kappa B2 (NFkB2) - RPB825Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Nuclear Factor Kappa B2 (NFkB2) - RPB825Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

NFKB2 protein-GST fusion - 009-001-S57 from Rockland Immunochemicals Inc

Category Protein
Prices $499.00
Sizes 50 µg
Species Human

NFKB2 protein-GST fusion - 009-001-S57S from Rockland Immunochemicals Inc

Category Protein
Prices $265.00
Sizes 20 µg
Species Human

NF-kappaB p100 Blocking Peptide - CBP1802 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Pig

NF-kappaB p100 (pS865) Blocking Peptide - CBP4123 from Cohesion Biosciences

Category Peptide
Prices $150.00, $450.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Chicken, Pig

NFkB-p100 (S865) Peptide - BS1246P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

NFkB-p100 (S869) Peptide - BS1247P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

p-NFkB-p100 (S865) Peptide - BS4129P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

p-NFkB-p100 (S869) Peptide - BS4130P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Nuclear Factor Kappa B2 (NFkB2) - RPB825Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human
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