ICA1

Gene Symbol	ICA1
Entrez Gene	3382
Alt Symbol	ICA69, ICAp69
Species	Human
Gene Type	protein-coding
Description	islet cell autoantigen 1, 69kDa
Other Description	69 kDa islet cell autoantigen|diabetes mellitus type I autoantigen|islet cell autoantigen 1|islet cell autoantigen 1 isoform|islet cell autoantigen p69|p69
Swissprots	Q96HG3 Q13824 P78506 Q05084 B3FTQ2 A8K7U1
Accessions	AAB19035 AAB94737 AAB94738 AAD50515 AAF20020 AAF20021 CAY55971 CAY55972 EAW93610 EAW93611 EAW93612 EAW93613 EAW93614 EAW93615 EAW93616 EAW93617 EAW93618 EAW93619 EAW93620 Q05084 AA581444 AI346099 AK292106 BAF84795 AM393016 CAL37894 BC005922 BC008640 AAH08640 BM716117 BU728575 DA076379 DA154134 DB010744 DB040266 DQ891505 ABM82431 EU176613 ABW03414 EU416199 ACB47390 L01100 AAA02564 L21181 AAA64927 U26591 AAB19033 U26592 AAB19034 U37183 AAC50935 U38260 AAC50936 XM_005249735 XP_005249792 XM_011515345 XP_011513647 XM_011515346 XP_011513648 XM_011515347 XP_011513649 XM_011515348 XP_011513650 XM_011515349 XP_011513651 XM_011515350 XP_011513652 XM_011515351 XP_011513653 XM_011515352 XP_011513654 XM_011515353 XP_011513655 XM_011515354 XP_011513656 XM_011515355 XP_011513657 XM_011515356 XP_011513658 XM_011515357 XP_011513659 XR_926934 XR_926935 NM_001136020 NP_001129492 NM_001276478 NP_001263407 NM_004968 NP_004959 NM_022307 NP_071682 NM_022308
Function	May play a role in neurotransmitter secretion. {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol {ECO:0000269|PubMed:12682071}. Golgi apparatus membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Tissue Specificity	Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
Top Pathways	Type I diabetes mellitus

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ICA1-Over-expression-Lysate - LY12774a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ICA1 293 Cell Lysate - 402543 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ICA1 293 Cell Lysate - 408249 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ICA1 Overexpression Lysate (Native) - NBL1-11801 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ICA1 Overexpression Lysate (Native) - NBL1-11802 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ICA1 Over-expression Lysate Product - GWB-A46990 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ICA1 Over-expression Lysate Product - GWB-280C05 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

ICA1 Overexpression Lysate (Native) - NBP2-09597 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ICA1 Overexpression Lysate (Denatured) - H00003382-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human ICA1 Knockdown Stable Cell Line - CSC-DC007380 from Creative biogene Category Cell Line Species Human

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