ICA1

Gene Symbol ICA1
Entrez Gene 3382
Alt Symbol ICA69, ICAp69
Species Human
Gene Type protein-coding
Description islet cell autoantigen 1, 69kDa
Other Description 69 kDa islet cell autoantigen|diabetes mellitus type I autoantigen|islet cell autoantigen 1|islet cell autoantigen 1 isoform|islet cell autoantigen p69|p69
Swissprots Q96HG3 Q13824 P78506 Q05084 B3FTQ2 A8K7U1
Accessions AAB19035 AAB94737 AAB94738 AAD50515 AAF20020 AAF20021 CAY55971 CAY55972 EAW93610 EAW93611 EAW93612 EAW93613 EAW93614 EAW93615 EAW93616 EAW93617 EAW93618 EAW93619 EAW93620 Q05084 AA581444 AI346099 AK292106 BAF84795 AM393016 CAL37894 BC005922 BC008640 AAH08640 BM716117 BU728575 DA076379 DA154134 DB010744 DB040266 DQ891505 ABM82431 EU176613 ABW03414 EU416199 ACB47390 L01100 AAA02564 L21181 AAA64927 U26591 AAB19033 U26592 AAB19034 U37183 AAC50935 U38260 AAC50936 XM_005249735 XP_005249792 XM_011515345 XP_011513647 XM_011515346 XP_011513648 XM_011515347 XP_011513649 XM_011515348 XP_011513650 XM_011515349 XP_011513651 XM_011515350 XP_011513652 XM_011515351 XP_011513653 XM_011515352 XP_011513654 XM_011515353 XP_011513655 XM_011515354 XP_011513656 XM_011515355 XP_011513657 XM_011515356 XP_011513658 XM_011515357 XP_011513659 XR_926934 XR_926935 NM_001136020 NP_001129492 NM_001276478 NP_001263407 NM_004968 NP_004959 NM_022307 NP_071682 NM_022308
Function May play a role in neurotransmitter secretion. {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12682071}. Golgi apparatus membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Tissue Specificity Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
Top Pathways Type I diabetes mellitus

Human-ICA1-cDNA-Clone - DC02444 from Abgent, a WuXi AppTec company

Prices $650.70
Sizes 10 µg
Species Human
Accession BC008640

ICA1 - MBS1274667 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC005922

ICA1 - MBS1266733 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC008640

Human ICA1 cDNA clone(NM_004968.2) - CDFH008928 from Creative Biomart

Species Human
Accession NM_004968.2

Human ICA1 ORF Clone(NM_001136020.1) - CDCL166728 from Creative Biomart

Species Human
Accession NM_001136020.1

Human ICA1 ORF Clone(NM_001136020.1) - CDCL166730 from Creative Biomart

Species Human
Accession NM_001136020.1

Human ICA1 ORF Clone(NM_001136020.1) - CDCL166731 from Creative Biomart

Species Human
Accession NM_001136020.1

Human ICA1 ORF Clone(NM_004968.2) - CDCR289302 from Creative Biomart

Species Human
Accession NM_004968.2

Human ICA1 ORF Clone(NM_004968.2) - CDCR289303 from Creative Biomart

Species Human
Accession NM_004968.2

Human ICA1 ORF Clone(NM_004968.2) - CDCR289304 from Creative Biomart

Species Human
Accession NM_004968.2

Human ICA1 ORF Clone(NM_001136020.1) - CDCR350543 from Creative Biomart

Species Human
Accession NM_001136020.1

Human ICA1 ORF Clone(NM_001136020.1) - CDCR350544 from Creative Biomart

Species Human
Accession NM_001136020.1

Human ICA1 ORF Clone(NM_004968.2) - CDCR289302 from Creative biogene

Species Human

Mouse ICA1 ORF clone (NM_001136020.1) - CDCL119127 from Creative biogene

Species Human

Human ICA1 ORF Clone (BC005922) - CDCS408154 from Creative biogene

Species Human
Accession Q05084

Human ICA1 ORF Clone (BC008640) - CDCS408155 from Creative biogene

Species Human
Accession Q05084

Human ICA1 cDNA Clone(NM_001136020.1) - CDFH008927 from Creative biogene

Species Human

Human ICA1 cDNA Clone(NM_004968.2) - CDFH008928 from Creative biogene

Species Human
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