| Gene Symbol | CHRM4 |
|---|---|
| Entrez Gene | 1132 |
| Alt Symbol | HM4, M4R |
| Species | Human |
| Gene Type | protein-coding |
| Description | cholinergic receptor, muscarinic 4 |
| Other Description | acetylcholine receptor, muscarinic 4|muscarinic acetylcholine receptor M4 |
| Swissprots | B2RPP4 P08173 Q4VBK7 Q0VD60 |
| Accessions | AAA51571 BAC05815 CAA33336 EAW68004 P08173 AF385590 AAK68115 AF498918 AAM18941 BC095546 AAH95546 BC119775 AAI19776 BC119817 AAI19818 BC137535 AAI37536 BF724332 BQ322895 NM_000741 NP_000732 |
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Top Pathways | Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction |