CHRM4

Gene Symbol	CHRM4
Entrez Gene	1132
Alt Symbol	HM4, M4R
Species	Human
Gene Type	protein-coding
Description	cholinergic receptor, muscarinic 4
Other Description	acetylcholine receptor, muscarinic 4|muscarinic acetylcholine receptor M4
Swissprots	B2RPP4 P08173 Q4VBK7 Q0VD60
Accessions	AAA51571 BAC05815 CAA33336 EAW68004 P08173 AF385590 AAK68115 AF498918 AAM18941 BC095546 AAH95546 BC119775 AAI19776 BC119817 AAI19818 BC137535 AAI37536 BF724332 BQ322895 NM_000741 NP_000732
Function	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Top Pathways	Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CHRM4 / M4 Antibody Blocking Peptide - LS-E28521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Muscarinic Acetylcholine Receptor M4/CHRM4 Protein - H00001132-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

Muscarinic acetylcholine receptor M4 - H00001132-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CHRM4 fusion protein - ag18067 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CHRM4 fusion protein - ag19191 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Muscarinic M4 Receptor - GWB-D6954B from Genway Biotech Category Peptide Prices $473.00 Sizes 250 µg Source Synthetic

mAChR M4 (P277) Peptide - BS3236P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

CHRM4 Peptide - abx164646 from Abbexa Category Peptide Species Human, Mouse

Muscarinic Receptor M4, Peptide - MBS658202 from MyBioSource Category Peptide Prices $565.00 Sizes 250 µg Source Synthetic

Muscarinic M4 Receptor Peptide (OEMA00042) - OEMA00042 from Aviva Systems Biology Category Peptide Prices $465.00 Sizes 250 µg

ChemiSCREEN™ Human Recombinant M4 Muscarinic Acetylcholine Receptor Calcium-Optimized Stable Cell Line - HTS117C from EMD Millipore Species Human

CHRM4-Blocking-Peptide-C-Term - BP21733b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CHRM4 Peptide, Human - M34GP03127H from Creative Peptides Category Peptide Source Synthetic. Species Human

Muscarinic acetylcholine receptor M4 (CHRM4), Recombinant Protein - MBS963142 from MyBioSource Category Protein Prices $790.00, $790.00, $1,015.00, $1,015.00, $1,050.00, $1,050.00, $1,510.00, $1,510.00, $1,510.00, $2,040.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Muscarinic acetylcholine receptor M4 (CHRM4), Recombinant Protein - MBS7011439 from MyBioSource Category Protein Prices $1,280.00, $2,265.00, $3,470.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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