| Gene Symbol |
CHRM4
|
| Entrez Gene |
1132
|
| Alt Symbol |
HM4, M4R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, muscarinic 4
|
| Other Description |
acetylcholine receptor, muscarinic 4|muscarinic acetylcholine receptor M4
|
| Swissprots |
B2RPP4 P08173 Q4VBK7 Q0VD60
|
| Accessions |
AAA51571 BAC05815 CAA33336 EAW68004 P08173 AF385590 AAK68115 AF498918 AAM18941 BC095546 AAH95546 BC119775 AAI19776 BC119817 AAI19818 BC137535 AAI37536 BF724332 BQ322895 NM_000741 NP_000732
|
| Function |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction
|
![Western Blot: Muscarinic Acetylcholine Receptor M4 Overexpression Lysate (Adult Normal) [NBP2-04174] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Muscarinic Acetylcholine Receptor M4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4216_Muscarinic%2520Acetylcholine%2520Receptor%2520M4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04174-img0001.jpg)