SSH1

Gene Symbol	SSH1
Entrez Gene	54434
Alt Symbol	SSH1L
Species	Human
Gene Type	protein-coding
Description	slingshot protein phosphatase 1
Other Description	SSH-like protein 1|hSSH-1L|protein phosphatase Slingshot homolog 1|slingshot homolog 1
Swissprots	Q6P6C0 Q8WYL4 Q8WYL5 Q8WYL3 Q9P2P8 Q8N9A7
Accessions	EAW97830 EAW97831 EAW97832 EAW97833 Q8WYL5 AB037719 BAA92536 AB072355 BAB84114 AB072356 BAB84115 AB072357 BAB84116 AI621348 AK025581 AK095421 BAC04546 BC005101 BC013792 BC020243 BC062341 AAH62341 BP363810 XM_005268984 XP_005269041 XM_005268985 XP_005269042 XM_005268986 XP_005269043 XM_006719466 XP_006719529 XM_011538497 XP_011536799 XM_011538498 XP_011536800 XM_011538499 XP_011536801 XM_011538500 XP_011536802 XM_011538501 XP_011536803 NM_001161330 NP_001154802 NM_001161331 NP_001154803 NM_018984 NP_061857
Function	Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. {ECO:0000269|PubMed:11832213, ECO:0000269|PubMed:12684437, ECO:0000269|PubMed:12807904, ECO:0000269|PubMed:14531860, ECO:0000269|PubMed:14645219, ECO:0000269|PubMed:15056216, ECO:0000269|PubMed:15159416, ECO:0000269|PubMed:15660133, ECO:0000269|PubMed:15671020, ECO:0000269|PubMed:16230460}.
Subcellular Location	Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion. Also localized to the cleavage furrow and the midbody during cytokinesis.
Top Pathways	Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Slingshot homolog 1 full length protein - ab153370 from Abcam Category Protein Source Wheat germ Species Human

Human Slingshot homolog 1 protein fragment - ab153371 from Abcam Category Protein Source Wheat germ Species Human

Human Slingshot homolog 1 protein fragment - ab153372 from Abcam Category Protein Source Wheat germ Species Human

SSH1 Antibody Blocking Peptide - LS-E6620 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SSH1 Protein - H00054434-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human SSH1 Protein - H00054434-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SSH1 Partial Recombinant Protein - H00054434-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

SSH1 Peptide - NBP1-64737 from Novus Biologicals Category Peptide Prices $269.00 Sizes 250 µg

SSH1-AntibodyN-term-Blocking-peptide - BP19412a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SSH1 - H00054434-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

SSH1 - H00054434-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SSH1 - H00054434-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SSH1 - H00054434-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

SSH1 - H00054434-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SSH1 - H00054434-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SSH1 control peptide - AP09872CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 100 µg

SSH1 fusion protein - Ag10250 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SSH1 fusion protein - Ag24579 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

SSH1 fusion protein - ag10274 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human SSH1, His-tagged - SSH1-2967H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Slingshot Homolog 1 (SSH1) - RPJ456Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Slingshot Homolog 1 (SSH1) - RPJ456Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Protein phosphatase Slingshot homolog 1(SSH1) ,partial - CSB-YP837881HU CSB-EP837881HU CSB-BP837881HU CSB-MP837881HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SSH1 Protein - NBP1-89604PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SSH1 Peptide, Human - M34GP15200H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more