SSH1

Gene Symbol SSH1
Entrez Gene 54434
Alt Symbol SSH1L
Species Human
Gene Type protein-coding
Description slingshot protein phosphatase 1
Other Description SSH-like protein 1|hSSH-1L|protein phosphatase Slingshot homolog 1|slingshot homolog 1
Swissprots Q6P6C0 Q8WYL4 Q8WYL5 Q8WYL3 Q9P2P8 Q8N9A7
Accessions EAW97830 EAW97831 EAW97832 EAW97833 Q8WYL5 AB037719 BAA92536 AB072355 BAB84114 AB072356 BAB84115 AB072357 BAB84116 AI621348 AK025581 AK095421 BAC04546 BC005101 BC013792 BC020243 BC062341 AAH62341 BP363810 XM_005268984 XP_005269041 XM_005268985 XP_005269042 XM_005268986 XP_005269043 XM_006719466 XP_006719529 XM_011538497 XP_011536799 XM_011538498 XP_011536800 XM_011538499 XP_011536801 XM_011538500 XP_011536802 XM_011538501 XP_011536803 NM_001161330 NP_001154802 NM_001161331 NP_001154803 NM_018984 NP_061857
Function Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. {ECO:0000269|PubMed:11832213, ECO:0000269|PubMed:12684437, ECO:0000269|PubMed:12807904, ECO:0000269|PubMed:14531860, ECO:0000269|PubMed:14645219, ECO:0000269|PubMed:15056216, ECO:0000269|PubMed:15159416, ECO:0000269|PubMed:15660133, ECO:0000269|PubMed:15671020, ECO:0000269|PubMed:16230460}.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion. Also localized to the cleavage furrow and the midbody during cytokinesis.
Top Pathways Regulation of actin cytoskeleton

SSH1 (E1K3W) Rabbit mAb - 13578 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1K3W
Western blot analysis of extracts from various cell lines using SSH1 (E1K3W) Rabbit mAb.

Anti-Slingshot homolog 1 antibody - ab76943 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Slingshot homolog 1 antibody (ab76943) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µg

Anti-Slingshot homolog 1 antibody - ab107799 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Slingshot homolog 1 antibody (ab107799) at 1 µg/mlLane 1 : Brain (Mouse) Tissue LysateLane 2 : Heart (Mouse) Tissue LysateLane 3 : A431 (Human epithelial carcinoma cell line) Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-SSH1 Antibody (aa725-775) - LS-C89268 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa675-725) - LS-C89267 from LifeSpan Bioscience

Prices $575.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa999-1049) - LS-C89269 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, APC) - LS-C241260 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, AP) - LS-C241261 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, Biotin) - LS-C241262 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, FITC) - LS-C241263 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, PE) - LS-C241264 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254, Azide-free, HRP) - LS-C248252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa675-725) - LS-C288117 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (clone 1D2) - LS-C139259 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2
SSH1 monoclonal antibody (M02), clone 1D2. Western blot of SSH1 expression in HeLa.

Anti-SSH1 Antibody (aa725-775) - LS-C288118 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa999-1049) - LS-C288119 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254) - LS-C325396 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SSH1 Antibody (aa226-254) - LS-C156139 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SSH1 Antibody western blot of HeLa cell line lysates (35 ug/lane). The SSH1 antibody detected the SSH1 protein (arrow).

SSH1 Antibody - NB100-60671 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SSH1 Antibody - NB100-60672 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SSH1 Antibody [NB100-60672] - Detection of Human SSH1 on HeLa whole cell lysate using NB100-60672. SSH1 was also immunoprecipitated by rabbit anti-SSH1 antibodies NB100-60671 and NB100-60673.

SSH1 Antibody - NB100-60673 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SSH1 Antibody [NB100-60673] - Detection of Human SSH1 on HeLa whole cell lysate using NB100-60673. SSH1 was also immunoprecipitated by rabbit anti-SSH1 antibodies NB100-60671 and NB100-60672.

SSH1 Antibody - H00054434-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SSH1 Antibody [H00054434-B01] - analysis of SSH1 expression in transfected 293T cell line by SSH1 MaxPab polyclonal antibody (B01). Lane1: SSH1 transfected lysate (115.50 KDa). Lane2: Non-transfected lysate.

SSH1 Antibody (2F9) - H00054434-M12 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F9

SSH1 Antibody (1D2) - H00054434-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2
Western Blot: SSH1 Antibody (1D2) [H00054434-M02] - SSH1 monoclonal antibody (M02), clone 1D2. Analysis of SSH1 expression in HeLa.

SSH1 Antibody - H00054434-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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