PSMG1

Gene Symbol	PSMG1
Entrez Gene	8624
Alt Symbol	C21LRP, DSCR2, LRPC21, PAC-1, PAC1
Species	Human
Gene Type	protein-coding
Description	proteasome (prosome, macropain) assembly chaperone 1
Other Description	Down syndrome critical region gene 2|Down syndrome critical region protein 2|chromosome 21 leucine-rich protein|leucine rich protein C21-LRP|proteasome assembling chaperone 1|proteasome assembly chaperone 1
Swissprots	Q6FHD3 B5BUN2 Q6FHA3 O95456 Q6S713
Accessions	CAB90451 EAX09664 EAX09665 EAX09666 O95456 AA731200 AB451468 BAG70282 AF417108 AJ006291 CAA06957 AK001455 AK308614 AK315406 BAG37798 AW594615 AY463963 AAR25628 BC003619 AAH03619 BC010424 AAH10424 BC011755 AAH11755 BC012809 AAH12809 BE779375 BM013494 BM460414 BM462074 BM476420 BQ008489 BR000236 FAA00022 CB160221 CR541821 CAG46620 CR541852 CAG46650 DQ892311 ABM83237 DQ895511 ABM86437 FN152980 XM_011529771 XP_011528073 NM_001261824 NP_001248753 NM_003720 NP_003711 NM_203433 NP_982257 NR_049728
Function	Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. {ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17707236}.
Subcellular Location	Cytoplasm. Endoplasmic reticulum.
Tissue Specificity	In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines. {ECO:0000269|PubMed:10872820, ECO:0000269|PubMed:9784380}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PSMG1 overexpression lysate - LY401225 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PSMG1 overexpression lysate - LY404289 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PSMG1 overexpression lysate - LY430925 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PSMG1 293 Cell Lysate - 401129 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PSMG1 Overexpression Lysate (Native) - NBL1-14911 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PSMG1 Over-expression Lysate Product - GWB-D49D71 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human PSMG1 Knockdown Stable Cell Line - CSC-DC012621 from Creative biogene Category Cell Line Species Human

PSMG1 KO Cell Lysate-HEK293T - CLKO-0881 from Creative biogene Category Cell Lysate

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