PSMG1

Gene Symbol PSMG1
Entrez Gene 8624
Alt Symbol C21LRP, DSCR2, LRPC21, PAC-1, PAC1
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) assembly chaperone 1
Other Description Down syndrome critical region gene 2|Down syndrome critical region protein 2|chromosome 21 leucine-rich protein|leucine rich protein C21-LRP|proteasome assembling chaperone 1|proteasome assembly chaperone 1
Swissprots Q6FHD3 B5BUN2 Q6FHA3 O95456 Q6S713
Accessions CAB90451 EAX09664 EAX09665 EAX09666 O95456 AA731200 AB451468 BAG70282 AF417108 AJ006291 CAA06957 AK001455 AK308614 AK315406 BAG37798 AW594615 AY463963 AAR25628 BC003619 AAH03619 BC010424 AAH10424 BC011755 AAH11755 BC012809 AAH12809 BE779375 BM013494 BM460414 BM462074 BM476420 BQ008489 BR000236 FAA00022 CB160221 CR541821 CAG46620 CR541852 CAG46650 DQ892311 ABM83237 DQ895511 ABM86437 FN152980 XM_011529771 XP_011528073 NM_001261824 NP_001248753 NM_003720 NP_003711 NM_203433 NP_982257 NR_049728
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. {ECO:0000269|PubMed:16251969, ECO:0000269|PubMed:17707236}.
Subcellular Location Cytoplasm. Endoplasmic reticulum.
Tissue Specificity In the adult, detected in brain, colon, leukocytes, breast and testis. Widely expressed in the fetus. Also expressed in a variety of proliferating cell lines. {ECO:0000269|PubMed:10872820, ECO:0000269|PubMed:9784380}.

PSMG1/PAC1 Antibody - 13378 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PSMG1/PAC1 Antibody.

DSCR 2 (L-15) - sc-83245 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-PSMG1 antibody - ab92278 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-PSMG1 antibody (ab92278) at 0.3 µg/ml + Jurkat cell lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-PSMG1 antibody - ab83527 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PSMG1 antibody (ab83527) at 1 µg/ml (in 5% skim milk/ PBS) + Human fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PSMG1 antibody [EPR10223] - ab167396 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10223
All lanes : Anti-PSMG1 antibody [EPR10223] (ab167396) at 1/10000 dilutionLane 1 : U-87 MG cell lysateLane 2 : Jurkat cell lysateLane 3 : 293T cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PSMG1 Antibody - LS-C307895 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PSMG1 Antibody (C-Terminus) - LS-C102189 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMG1 antibody LS-C102189 Western blot of Fetal Heart lysate.

Anti-PSMG1 Antibody (C-Terminus) - LS-C112794 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PSMG1 antibody (0.3 ug/ml) staining of Jurkat lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PSMG1 Antibody (aa144-193) - LS-C111067 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMG1 antibody LS-C111067 Western blot of MCF7 cell lysate.

PSMG1 Antibody - NBP1-52843 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PSMG1 Antibody [NBP1-52843] - Human Heart lysate, concentration 0.2-1 ug/ml.

PSMG1 Antibody - NBP2-33820 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PSMG1 Antibody [NBP2-33820] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & the Golgi apparatus.

PSMG1 Antibody (4F2) - H00008624-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F2
Sandwich ELISA: PSMG1 Antibody (4F2) [H00008624-M01] - Detection limit for recombinant GST tagged DSCR2 is approximately 0.03ng/ml as a capture antibody.

PSMG1 Antibody - NBP1-36951 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: PSMG1 Antibody [NBP1-36951] - Analysis of PSMG1 in Jurkat lysate (35ug protein in RIPA buffer) using this antibody at 0.3ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

PSMG1 Antibody - NBP2-19994 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PSMG1 Antibody [NBP2-19994] - Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE gel, diluted at 1:2000.

PSMG1 Antibody (4B9) - H00008624-M03-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B9

Anti-PSMG1 antibody produced in rabbit - HPA057193 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSMG1: <B>Cat. No. HPA057193</B>: Immunohistochemical staining of Human cerebellum shows strong granular cytoplasmic positivity in Purkinje cells.

Anti-PSMG1 (ab2) antibody produced in rabbit - SAB2101903 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSMG1 (ab2): <B>Cat. No.SAB2101903</B>: PSMG1 in MCF7 cell lysate with PSMG1 antibody at 1.0 μg/mL.

Anti-PSMG1 (C-terminal) antibody produced in goat - SAB2501217 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSMG1 (C-terminal): <B>Cat. No. SAB2501217</B>: (0.3 μg/mL) staining of Jurkat lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PSMG1 (ab1) antibody produced in rabbit - SAB2101902 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSMG1 (ab1): <B>Cat. No.SAB2101902</B>: PSMG1 in Fetal Heart tissue lysate with PSMG1 antibody at 1.0 μg/mL.

Monoclonal Anti-DSCR2 antibody produced in mouse - WH0008624M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F2
<B>Sandwich ELISA</B><BR/>Monoclonal Anti-DSCR2, <B>Cat. No. WH0008624M1</B>: the detection limit for recombinant GST tagged DSCR2 is approximately 0.03ng/mL.

PSMG1 antibody - middle region (ARP45813_P050) - ARP45813_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PSMG1 antibody - middle region (ARP45814_P050) - ARP45814_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DSCR2-Antibody-monoclonal-M01 - AT1821a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F2
Detection limit for recombinant GST tagged DSCR2 is approximately 0.03ng/ml as a capture antibody.

DSCR2--PSMG1-Antibody-C-Term - AF2907a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2907a (0.3 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

PSMG1 antibody, C-term - GTX47556 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-DSCR2 / PSMG1 antibody, C-term used in Western blot. GTX47556
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