PPRC1

Gene Symbol PPRC1
Entrez Gene 23082
Alt Symbol PRC
Species Human
Gene Type protein-coding
Description peroxisome proliferator-activated receptor gamma, coactivator-related 1
Other Description PGC-1-related coactivator|peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Swissprots Q9BUJ3 Q9Y4E0 Q5VV67 Q76N31 Q6P3U5 Q5VV66 Q9BZE5 Q6P3W1
Accessions EAW49719 EAW49720 EAW49721 Q5VV67 AB011167 BAA25521 AF325193 AAK11573 AK025691 AK095248 AK299885 BAG61732 BC002561 AAH02561 BC063806 AAH63806 BC063829 AAH63829 BU742486 CA442653 HY023373 XM_005269656 XP_005269713 XM_005269658 XP_005269715 XM_006717731 XP_006717794 XM_011539549 XP_011537851 XM_011539550 XP_011537852 XM_011539551 XP_011537853 XM_011539552 XP_011537854 XM_011539553 XP_011537855 NM_001288727 NP_001275656 NM_001288728 NP_001275657 NM_015062 NP_055877
Function Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes. {ECO:0000269|PubMed:11340167, ECO:0000269|PubMed:16908542}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11340167}. Note=Colocalizes with NRF1. {ECO:0000250}.
Tissue Specificity Strongly expressed in heart and skeletal muscle, moderately in lung, placenta, intestine, liver, kidney, spleen, thymus, colon and brain. Also expressed in several oncocytic thyroid tumors. {ECO:0000269|PubMed:11340167, ECO:0000269|PubMed:14550271}.

Panoply™ Human PPRC1 Knockdown Stable Cell Line - CSC-DC012299 from Creative biogene

Category Cell Line
Species Human
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