Gene Symbol | NEU3 |
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Entrez Gene | 10825 |
Alt Symbol | SIAL3 |
Species | Human |
Gene Type | protein-coding |
Description | sialidase 3 (membrane sialidase) |
Other Description | N-acetyl-alpha-neuraminidase 3|ganglioside sialidase|membrane sialidase|neuraminidase 3|sialidase-3 |
Swissprots | Q9NQE1 A8K327 Q9UQ49 |
Accessions | EAW74953 EAW74954 Q9UQ49 AB008185 BAA82611 AK022450 BAG51074 AK290442 BAF83131 AK303540 BAG64566 BC136397 AAI36398 BC144059 AAI44060 CN429425 DB240271 DQ590342 Y18563 CAB96131 NM_006656 NP_006647 |
Function | Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. {ECO:0000269|PubMed:10861246, ECO:0000269|PubMed:20511247}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:10861246}; Peripheral membrane protein {ECO:0000269|PubMed:10861246}. |
Tissue Specificity | Highly expressed in skeletal muscle, testis, adrenal gland and thymus, followed by pancreas, liver, heart and thymus. Weakly expressed in kidney, placenta, brain and lung. {ECO:0000269|PubMed:10861246}. |
Top Pathways | Sphingolipid metabolism, Other glycan degradation |
Ganglioside sialidase (H-75) - sc-134930 from Santa Cruz Biotechnology
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Ganglioside sialidase (M-50) - sc-134931 from Santa Cruz Biotechnology
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Ganglioside sialidase (K-19) - sc-55825 from Santa Cruz Biotechnology
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Ganglioside sialidase (N-18) - sc-55826 from Santa Cruz Biotechnology
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Anti-Sialidase-3 antibody - ab80541 from Abcam
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Anti-NEU3 Antibody (C-Terminus) - LS-C186739 from LifeSpan Bioscience
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Anti-NEU3 Antibody (clone 11B) - LS-C179421 from LifeSpan Bioscience
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NEU3 Antibody - 21630002 from Novus Biologicals
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NEU3 Antibody - NBP2-32644 from Novus Biologicals
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Anti-NEU3 antibody produced in rabbit - HPA038729 from Sigma-Aldrich
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Anti-NEU3 antibody produced in rabbit - HPA038730 from Sigma-Aldrich
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NEU3 Antibody - C-terminal region (ARP64046_P050) - ARP64046_P050 from Aviva Systems Biology
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Sialidase 3 antibody - orb186135 from Biorbyt
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Sialidase-3 antibody (Biotin) - orb243858 from Biorbyt
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Sialidase-3 Antibody - abx110648 from Abbexa
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Sialidase-3 Antibody (Biotin) - abx106383 from Abbexa
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Sialidase-3 Antibody (FITC) - abx107795 from Abbexa
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Sialidase-3 Antibody (HRP) - abx109213 from Abbexa
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Sialidase-3 antibody - AM26497AF-N from Acris Antibodies
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Anti-Bacteria Sialidase Polyclonal antibody - DPABY-077 from Creative Diagnostics
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Rabbit anti-human Sialidase-3 polyclonal Antibody; HRP conjugated - CSB-PA172674B0Rb from Cusabio
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Rabbit anti-human Sialidase-3 polyclonal Antibody;FITC conjugated - CSB-PA172674C0Rb from Cusabio
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Rabbit anti-human Sialidase-3 polyclonal Antibody;Biotin conjugated - CSB-PA172674D0Rb from Cusabio
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Rabbit anti-human Sialidase-3 polyclonal Antibody - CSB-PA172674A0Rb from Cusabio
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NEU3-Antibody-C-terminal-region-AI15054 - AI15054 from Abgent, a WuXi AppTec company
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