| Gene Symbol | NEU3 |
|---|---|
| Entrez Gene | 10825 |
| Alt Symbol | SIAL3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | sialidase 3 (membrane sialidase) |
| Other Description | N-acetyl-alpha-neuraminidase 3|ganglioside sialidase|membrane sialidase|neuraminidase 3|sialidase-3 |
| Swissprots | Q9NQE1 A8K327 Q9UQ49 |
| Accessions | EAW74953 EAW74954 Q9UQ49 AB008185 BAA82611 AK022450 BAG51074 AK290442 BAF83131 AK303540 BAG64566 BC136397 AAI36398 BC144059 AAI44060 CN429425 DB240271 DQ590342 Y18563 CAB96131 NM_006656 NP_006647 |
| Function | Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. {ECO:0000269|PubMed:10861246, ECO:0000269|PubMed:20511247}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:10861246}; Peripheral membrane protein {ECO:0000269|PubMed:10861246}. |
| Tissue Specificity | Highly expressed in skeletal muscle, testis, adrenal gland and thymus, followed by pancreas, liver, heart and thymus. Weakly expressed in kidney, placenta, brain and lung. {ECO:0000269|PubMed:10861246}. |
| Top Pathways | Sphingolipid metabolism, Other glycan degradation |