Gene Symbol | UGT1A10 |
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Entrez Gene | 54575 |
Alt Symbol | UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J |
Species | Human |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 1 family, polypeptide A10 |
Other Description | UDP glycosyltransferase 1 family, polypeptide A10|UDP-glucuronosyltransferase 1-10|UDP-glucuronosyltransferase 1-J|UDP-glucuronosyltransferase 1A10|UDPGT 1-10 |
Swissprots | Q9HAW8 O00474 Q6NT91 Q7Z6H8 |
Accessions | AAA80547 AAF03522 AAG30417 EAW71058 Q9HAW8 AK025403 AY435137 AAR95638 BC020971 AAH20971 BC053576 AAH53576 BC069210 AAH69210 U89508 AAB81537 NM_019075 NP_061948 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:19545173}. |
Subcellular Location | Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Liver and colon. Isoform 1 and isoform 2 are expressed in colon, esophagus and small intestine; isoform 2 but not isoform 1 is expressed in liver or kidney (PubMed:18004212). {ECO:0000269|PubMed:18004212, ECO:0000269|PubMed:9271343}. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
UGT1A (B-4) - sc-271268 from Santa Cruz Biotechnology
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Anti-UGT1A10 antibody - ab76677 from Abcam
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Anti-UGT1A10 antibody - ab194474 from Abcam
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Anti-UGT1A10 antibody - ab197117 from Abcam
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UGT1A10 Antibody - H00054575-A01 from Novus Biologicals
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UGT1A10 Antibody (2D3) - H00054575-M02 from Novus Biologicals
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Monoclonal Anti-UGT1A10 antibody produced in mouse - SAB1403273 from Sigma-Aldrich
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UGT1A10 Antibody - abx036577 from Abbexa
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UGT1A10 antibody - H00054575-A01 from Acris Antibodies
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UGT1A10 antibody - H00054575-M02 from Acris Antibodies
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Mouse Anti-Human UGT1A10 - 101-11892 from RayBiotech
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UGT1A10 antibody - 14457-1-AP from Proteintech Group
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UGT1A10 Antibody - E307337 from Enogene
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UGT1A10, Monoclonal Antibody - MBS646813 from MyBioSource
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Anti-UGT1A10 (aa 187-289) polyclonal antibody - DPAB-DC2342 from Creative Diagnostics
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UGT1A10, Polyclonal Antibody - MBS8500036 from MyBioSource
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Anti-UDP glucuronosyltransferase 1 family, polypeptide A10 - 08A054575 from MP Biomedicals
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UGT1A10 Antibody - 42804 from Signalway Antibody
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UGT1A10 Antibody - CSB-PA227642 from Cusabio
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UGT1A10 Antibody - CSB-PA451449 from Cusabio
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UGT1A10 antibody - orb360094 from Biorbyt
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UGT1A10 antibody - TA350572 from Acris Antibodies
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UGT1A10 Polyclonal Antibody - E-AB-17203 from Elabscience
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UGT1A10 Polyclonal Antibody - E-AB-17202 from Elabscience
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UGT1A10 antibody - N - terminal region (OAAB11674) - OAAB11674 from Aviva Systems Biology
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