| Gene Symbol |
THEM5
|
| Entrez Gene |
284486
|
| Alt Symbol |
ACOT15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thioesterase superfamily member 5
|
| Other Description |
acyl-CoA thioesterase THEM5|acyl-coenzyme A thioesterase 15|acyl-coenzyme A thioesterase THEM5
|
| Swissprots |
Q5T1C3 Q8N1Q8
|
| Accessions |
EAW53404 Q8N1Q8 AK095283 BAC04521 BC101610 AAI01611 BC112239 AAI12240 HQ258137 ADR82891 XM_011509421 XP_011507723 NM_182578 NP_872384
|
| Function |
Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function. {ECO:0000269|PubMed:22586271}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000269|PubMed:22586271}.
|