Gene Symbol | THEM5 |
---|---|
Entrez Gene | 284486 |
Alt Symbol | ACOT15 |
Species | Human |
Gene Type | protein-coding |
Description | thioesterase superfamily member 5 |
Other Description | acyl-CoA thioesterase THEM5|acyl-coenzyme A thioesterase 15|acyl-coenzyme A thioesterase THEM5 |
Swissprots | Q5T1C3 Q8N1Q8 |
Accessions | EAW53404 Q8N1Q8 AK095283 BAC04521 BC101610 AAI01611 BC112239 AAI12240 HQ258137 ADR82891 XM_011509421 XP_011507723 NM_182578 NP_872384 |
Function | Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function. {ECO:0000269|PubMed:22586271}. |
Subcellular Location | Mitochondrion matrix {ECO:0000269|PubMed:22586271}. |