Gene Symbol | TCEB2 |
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Entrez Gene | 6923 |
Alt Symbol | ELOB, SIII |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) |
Other Description | RNA polymerase II transcription factor SIII p18 subunit|RNA polymerase II transcription factor SIII subunit B|SIII p18|elongin 18 kDa subunit|elongin, 18-kD subunit|elongin-B|transcription elongation factor B polypeptide 2 |
Swissprots | B7WPD3 Q15370 |
Accessions | AAC08452 EAW85472 EAW85473 EAW85474 EAW85475 EAW85476 Q15370 AI191983 BC013306 AAH13306 BC065000 AAH65000 BF967495 BG329435 BM553320 BM700019 BM921799 BU533433 DT217333 EU447012 ABZ92541 L42856 AAA75522 NM_007108 NP_009039 NM_207013 NP_996896 |
Function | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Ubiquitin mediated proteolysis, Renal cell carcinoma |
Human TCEB2 full length protein - ab81767 from Abcam
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Human TCEB2 full length protein - ab117680 from Abcam
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TCEB2 / Elongin B Antibody Blocking Peptide - LS-E3174 from LifeSpan Bioscience
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TCEB2 / Elongin B Antibody Blocking Peptide - LS-E3828 from LifeSpan Bioscience
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TCEB2 / Elongin B Antibody Blocking Peptide - LS-E10941 from LifeSpan Bioscience
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TCEB2 Recombinant Protein - H00006923-P01 from Novus Biologicals
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TCEB2 Partial Recombinant Protein - H00006923-Q01 from Novus Biologicals
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Recombinant Human TCEB2 Protein - NBC1-22579 from Novus Biologicals
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TCEB2-Antibody-Center-Blocking-Peptide - BP14322c from Abgent, a WuXi AppTec company
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TCEB2-Antibody-N-term-Blocking-Peptide - BP16007a from Abgent, a WuXi AppTec company
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TCEB2 Protein (OPPA01823) - OPPA01823 from Aviva Systems Biology
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Human Transcription Elongation Factor Polypeptide protein - orb81411 from Biorbyt
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Elongin B protein - 30R-1236 from Fitzgerald
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TCEB2 Blocking Peptide - 33R-8982 from Fitzgerald
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TCEB2 (1-118) (recombinant) - AR50029PU-N from Acris Antibodies
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TCEB2 (1-118) (recombinant) - AR50029PU-S from Acris Antibodies
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TCEB2 - H00006923-P01-02 from Acris Antibodies
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TCEB2 - H00006923-Q01-10 from Acris Antibodies
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TCEB2 - H00006923-Q01-25 from Acris Antibodies
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Transcription Elongation Factor B Polypeptide 2, Human Recombinant - 228-11485-1 from RayBiotech
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Recombinant Human TCEB2 - 228-11485-2 from RayBiotech
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Recombinant Human TCEB2 - 228-11485-3 from RayBiotech
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Elongin B, 1-118aa, Human, Recombinant, E.coli - 01-2008 from ARP American Research Products
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TCEB2 fusion protein - Ag1228 from Proteintech Group
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Recombinant Human TCEB2 Protein - BP002022-PRO-664 from Syd Labs
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