APOC3

Gene Symbol APOC3
Entrez Gene 345
Alt Symbol APOCIII, HALP2
Species Human
Gene Type protein-coding
Description apolipoprotein C-III
Other Description apo-CIII|apoC-III|apolipoprotein C3
Swissprots Q08E83 P02656 Q6Q786
Accessions AAB59372 AAB59515 AAQ91810 AAS68230 ACA05940 ACA05941 ACA05942 AJA40867 CAA25648 CAA26895 CAI23899 CDM21968 EAW67272 EAW67273 P02656 BC027977 AAH27977 BC121081 AAI21082 BC134419 AAI34420 DQ892044 ABM82970 DQ895238 ABM86164 M28613 AAA51760 M28614 AAA51761 V01513 CAA24757 X00567 CAA25233 X01388 CAA25644 NM_000040 NP_000031
Function Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. {ECO:0000303|PubMed:18201179, ECO:0000303|PubMed:22510806}.
Subcellular Location Secreted {ECO:0000303|PubMed:18201179, ECO:0000303|PubMed:22510806}.
Tissue Specificity Liver. {ECO:0000269|PubMed:6328445}.
Top Pathways PPAR signaling pathway

apoC-III CRISPR/Cas9 KO Plasmid (h) - sc-403887 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III HDR Plasmid (h) - sc-403887-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III Double Nickase Plasmid (h) - sc-403887-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III Double Nickase Plasmid (h2) - sc-403887-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III CRISPR Activation Plasmid (h) - sc-403887-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III CRISPR Activation Plasmid (h2) - sc-403887-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III Lentiviral Activation Particles (h) - sc-403887-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III Lentiviral Activation Particles (h2) - sc-403887-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

apoC-III siRNA (h) - sc-41186 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

apoC-III shRNA Plasmid (h) - sc-41186-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

apoC-III shRNA (h) Lentiviral Particles - sc-41186-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU110451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3344 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3344 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00597 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00597

APOC3 siRNA (Human) - CRH0243 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APOC3 - MBS8211104 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APOC3 (NM_000040.1) - SHH238506 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APOC3(NM_000040.1) - SHG065743 from Creative biogene

Category siRNA
Species Reactivities Human

APOC3 shRNA Plasmid (Human) - CHH0243 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APOC3 miRNA 3'UTR clone - MiUTR1H-00478 from Creative biogene

Species Reactivities Human
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