APOC3

Gene Symbol	APOC3
Entrez Gene	345
Alt Symbol	APOCIII, HALP2
Species	Human
Gene Type	protein-coding
Description	apolipoprotein C-III
Other Description	apo-CIII|apoC-III|apolipoprotein C3
Swissprots	Q08E83 P02656 Q6Q786
Accessions	AAB59372 AAB59515 AAQ91810 AAS68230 ACA05940 ACA05941 ACA05942 AJA40867 CAA25648 CAA26895 CAI23899 CDM21968 EAW67272 EAW67273 P02656 BC027977 AAH27977 BC121081 AAI21082 BC134419 AAI34420 DQ892044 ABM82970 DQ895238 ABM86164 M28613 AAA51760 M28614 AAA51761 V01513 CAA24757 X00567 CAA25233 X01388 CAA25644 NM_000040 NP_000031
Function	Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. {ECO:0000303|PubMed:18201179, ECO:0000303|PubMed:22510806}.
Subcellular Location	Secreted {ECO:0000303|PubMed:18201179, ECO:0000303|PubMed:22510806}.
Tissue Specificity	Liver. {ECO:0000269|PubMed:6328445}.
Top Pathways	PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Apolipoprotein CIII full length protein - ab77944 from Abcam Category Protein Prices $356.00 Sizes 100 µg Source Native Species Human

Human Apolipoprotein CIII full length protein - ab167787 from Abcam Category Protein Prices $522.00 Sizes 100 µg Source Native Species Human

Human Apolipoprotein CIII peptide - ab103556 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Apolipoprotein CIII protein fragment - ab157899 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

APOC3 / Apolipoprotein C III Antibody Blocking Peptide - LS-E26814 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Apolipoprotein CIII Partial Recombinant Protein - H00000345-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Apolipoprotein CIII Protein - NBP1-99294 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg

Apolipoprotein CIII Human Expressed Protein - P4280 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Source Human Species Human

Human Apolipoprotein CIII Protein (OPMA04192) - OPMA04192 from Aviva Systems Biology Category Protein Prices $155.00 Sizes 100 µg Source Human plasma, Very Low Density Lipoprotein (VLDL) Species Human

Human APOC3 protein - orb244025 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human Apoc3 protein - orb245749 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

ApoC-III protein - 30-AA28 from Fitzgerald Category Protein Prices $195.00 Sizes 100 µg

ApoC3 protein - 30R-2679 from Fitzgerald Category Protein Prices $245.00 Sizes 100 µg Species Human

ApoC3 protein - 30-1052 from Fitzgerald Category Protein Prices $525.00 Sizes 100 µg Species Human

Apolipoprotein C3 Blocking Peptide - abx161274 from Abbexa Category Peptide Species Human, Mouse, Rat

Apolipoprotein C III / ApoC3 - BA057 from Acris Antibodies Category Protein Prices $205.00 Sizes 100 µg Source Plasma Species Human

Apolipoprotein C III (Apo CIII) - H00000345-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Apolipoprotein C III (Apo CIII) - H00000345-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Apolipoprotein C III (Apo CIII) - P4280 from Acris Antibodies Category Protein Prices $580.00 Sizes 100 µg Species Human

Human Apolipoprotein CIII - MD-26-0013P from RayBiotech Category Protein Source Human Plasma Species Human

Apolipoprotein C-III (APO-C-III) - GWB-E6FA58 from Genway Biotech Category Protein Prices $474.00 Sizes 100 µg

Human Apolipoprotein CIII - GWB-159883 from Genway Biotech Category Protein Prices $153.00 Sizes 100 µg Source Human Plasma, Very Low Density Lipoprotein (VLDL) Species Human

Recombinant Human Apolipoprotein C-III - APOC3-4905H from Creative Biomart Category Protein Source Human Plasma Species Human

Native Human ApoLipoprotein CIII - APOC3-8040H from Creative Biomart Category Protein Source Human Plasma Species Human

Native Human ApoC-III - ApoC-III-3559H from Creative Biomart Category Protein Source Human plasma Species Human

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