Gene Symbol | GAS2 |
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Entrez Gene | 2620 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | growth arrest-specific 2 |
Other Description | GAS-2|growth arrest-specific protein 2 |
Swissprots | Q7Z3X8 O43903 Q6ICV8 D3DQZ0 B2R9C8 |
Accessions | EAW68317 EAW68318 O43903 AI374985 AK313734 BAG36475 AU099094 BC005077 AAH05077 BC013326 AAH13326 BC040470 AAH40470 CR450285 CAG29281 DA345287 U95032 AAC52058 XM_011519971 XP_011518273 XM_011519972 XP_011518274 XM_011519973 XP_011518275 XM_011519974 XP_011518276 XM_011519975 XP_011518277 XM_011519976 XP_011518278 XM_011519977 XP_011518279 XM_011519978 XP_011518280 XM_011519979 XP_011518281 NM_001143830 NP_001137302 NM_005256 NP_005247 NM_177553 NP_808221 |
Function | May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth- arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen. |
Human GAS2 full length protein - ab158499 from Abcam
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Human GAS2 protein fragment - ab158500 from Abcam
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GAS2 Antibody Blocking Peptide - LS-E6244 from LifeSpan Bioscience
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Recombinant Human GAS2 Protein - H00002620-Q01 from Novus Biologicals
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Recombinant Human GAS2 Protein - H00002620-P01 from Novus Biologicals
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GAS2-Antibody-N-term-Blocking-Peptide - BP18918a from Abgent, a WuXi AppTec company
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Human GAS2 Protein - abx066927 from Abbexa
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GAS2 - H00002620-P01-10 from Acris Antibodies
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GAS2 - H00002620-P01-25 from Acris Antibodies
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GAS2 - H00002620-Q01-10 from Acris Antibodies
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GAS2 - H00002620-Q01-25 from Acris Antibodies
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GAS2 fusion protein - Ag2540 from Proteintech Group
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Recombinant Growth Arrest Specific Protein 2 (GAS2) - RPA201Hu01 from Uscn Life Science Inc.
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Recombinant Human Growth arrest-specific protein 2(GAS2) - CSB-YP009265HU CSB-EP009265HU CSB-BP009265HU CSB-MP009265HU from Cusabio
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GAS2 (transcript variant 2) - TP305912 from Acris Antibodies
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GAS2 (transcript variant 1) - TP323624 from Acris Antibodies
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GAS2 (transcript variant 3) - TP326863 from Acris Antibodies
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GAS2 Protein - NBP2-31733PEP from Novus Biologicals
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GAS2 Peptide, Human - M34GP06112H from Creative Peptides
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GAS2 Recombinant Protein (OPCD03441) - OPCD03441 from Aviva Systems Biology
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Growth Arrest Specific Protein 2 (GAS2), Recombinant Protein - MBS2018356 from MyBioSource
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Growth arrest-specific protein 2 (GAS2), Recombinant Protein - MBS1185190 from MyBioSource
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Recombinant Human GAS2 Protein, His-tagged - GAS2-190H from Creative Biomart
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Recombinant Human GAS2 Protein, GST-tagged - GAS2-4733H from Creative Biomart
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