| Gene Symbol |
AKAP1
|
| Entrez Gene |
8165
|
| Alt Symbol |
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
A kinase (PRKA) anchor protein 1
|
| Other Description |
A-kinase anchor protein 1, mitochondrial|A-kinase anchor protein 149 kDa|AKAP 149|D-AKAP-1|dual-specificity A-kinase anchoring protein 1|protein kinase A anchoring protein 1|protein kinase A1|protein phosphatase 1, regulatory subunit 43|spermatid A-kinase anchor protein 84|tudor domain containing 17
|
| Swissprots |
Q13320 D3DTZ0 Q9BW14 Q92667 A8K8Q1
|
| Accessions |
EAW94515 EAW94516 EAW94517 EAW94518 Q92667 AF015910 AAB64298 AK292416 BAF85105 AK297810 BAG60148 AK308397 BC000729 AAH00729 BM711930 CB048239 CD172211 DA092401 DA455114 DQ893602 ABM84528 EU176646 ABW03447 U34074 AAC50279 X97335 CAA66000 XM_005257707 XP_005257764 XM_005257709 XP_005257766 XM_011525318 XP_011523620 NM_001242902 NP_001229831 NM_001242903 NP_001229832 NM_003488 NP_003479 NM_139275
|
| Function |
Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.
|
| Subcellular Location |
Mitochondrion outer membrane {ECO:0000305}.
|
| Tissue Specificity |
AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.
|
![Western Blot: AKAP1 Overexpression Lysate [H00008165-T01] - Lane 1: AKAP1 transfected lysate (99.44 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/27508_AKAP1%2520Overexpression%2520Lysate-Western%2520Blot-H00008165-T01-img0001.jpg)
![Western Blot: AKAP1 Overexpression Lysate (Adult Normal) [NBL1-07424] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AKAP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7400_AKAP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07424-img0002.jpg)