Gene Symbol | AKAP1 |
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Entrez Gene | 8165 |
Alt Symbol | AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17 |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 1 |
Other Description | A-kinase anchor protein 1, mitochondrial|A-kinase anchor protein 149 kDa|AKAP 149|D-AKAP-1|dual-specificity A-kinase anchoring protein 1|protein kinase A anchoring protein 1|protein kinase A1|protein phosphatase 1, regulatory subunit 43|spermatid A-kinase anchor protein 84|tudor domain containing 17 |
Swissprots | Q13320 D3DTZ0 Q9BW14 Q92667 A8K8Q1 |
Accessions | EAW94515 EAW94516 EAW94517 EAW94518 Q92667 AF015910 AAB64298 AK292416 BAF85105 AK297810 BAG60148 AK308397 BC000729 AAH00729 BM711930 CB048239 CD172211 DA092401 DA455114 DQ893602 ABM84528 EU176646 ABW03447 U34074 AAC50279 X97335 CAA66000 XM_005257707 XP_005257764 XM_005257709 XP_005257766 XM_011525318 XP_011523620 NM_001242902 NP_001229831 NM_001242903 NP_001229832 NM_003488 NP_003479 NM_139275 |
Function | Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000305}. |
Tissue Specificity | AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma. |
AKAP 149 CRISPR/Cas9 KO Plasmid (h) - sc-403278 from Santa Cruz Biotechnology
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AKAP 149 HDR Plasmid (h) - sc-403278-HDR from Santa Cruz Biotechnology
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AKAP 149 Double Nickase Plasmid (h) - sc-403278-NIC from Santa Cruz Biotechnology
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AKAP 149 Double Nickase Plasmid (h2) - sc-403278-NIC-2 from Santa Cruz Biotechnology
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AKAP 149 CRISPR Activation Plasmid (h) - sc-403278-ACT from Santa Cruz Biotechnology
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AKAP 149 CRISPR Activation Plasmid (h2) - sc-403278-ACT-2 from Santa Cruz Biotechnology
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AKAP 149 Lentiviral Activation Particles (h) - sc-403278-LAC from Santa Cruz Biotechnology
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AKAP 149 Lentiviral Activation Particles (h2) - sc-403278-LAC-2 from Santa Cruz Biotechnology
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AKAP 149 siRNA (h) - sc-40301 from Santa Cruz Biotechnology
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AKAP 149 shRNA Plasmid (h) - sc-40301-SH from Santa Cruz Biotechnology
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AKAP 149 shRNA (h) Lentiviral Particles - sc-40301-V from Santa Cruz Biotechnology
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AKAP1 RNAi - H00008165-R01 from Novus Biologicals
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AKAP1 RNAi - H00008165-R02 from Novus Biologicals
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MISSION® esiRNA - EHU123321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3001 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07888 from Sigma-Aldrich
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AKAP1 siRNA (Human) - CRH5383 from Cohesion Biosciences
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AKAP1 - MBS8209747 from MyBioSource
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shRNA set against Human AKAP1 (NM_003488.3) - SHH234162 from Creative biogene
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shRNA set against Human AKAP1(NM_003488.3) - SHG049681 from Creative biogene
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Human AKAP1 siRNA - orb265885 from Biorbyt
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AKAP1 shRNA Plasmid (Human) - CHH5383 from Cohesion Biosciences
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AKAP1 miRNA 3'UTR clone - MiUTR1H-00263 from Creative biogene
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