Gene Symbol | AGBL1 |
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Entrez Gene | 123624 |
Alt Symbol | CCP4, FECD8 |
Species | Human |
Gene Type | protein-coding |
Description | ATP/GTP binding protein-like 1 |
Other Description | cytosolic carboxypeptidase 4 |
Swissprots | C9JHL5 A1A4X5 Q96MI9 A6NJH6 |
Accessions | EAX01983 EAX01984 Q96MI9 AK056872 BAB71299 BC128152 AAI28153 DA695799 DV080155 DV080218 DV080486 DV080541 DY655391 DY655510 XM_011521226 XP_011519528 XM_011521227 XP_011519529 XM_011521228 XP_011519530 XM_011521229 XP_011519531 XM_011521230 XP_011519532 XR_931750 XR_931751 NM_152336 NP_689549 |
Function | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. {ECO:0000250|UniProtKB:Q09M05}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:24094747}. |
Tissue Specificity | Expressed in corneal endothelium. {ECO:0000269|PubMed:24094747}. |
CCP4 (E-19) - sc-246224 from Santa Cruz Biotechnology
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CCP4 (S-17) - sc-246222 from Santa Cruz Biotechnology
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Anti-AGBL1 antibody - ab106237 from Abcam
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Anti-AGBL1 antibody - N-terminal - ab199151 from Abcam
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Anti-AGBL1 Antibody (aa748-761) - LS-C154861 from LifeSpan Bioscience
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AGBL1 Antibody - NBP1-93878 from Novus Biologicals
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Anti-AGBL1 antibody produced in rabbit - SAB4301031 from Sigma-Aldrich
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Anti-AGBL1 antibody produced in rabbit - HPA039653 from Sigma-Aldrich
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CCP4-aa748-761-Antibody-internal-region - AF3593a from Abgent, a WuXi AppTec company
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AGBL1 antibody - orb77504 from Biorbyt
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Goat anti-CCP4 (aa748-761) middle region Antibody (OAEB02845) - OAEB02845 from Aviva Systems Biology
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) - 208051 from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (AP) - 208051-AP from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (APC) - 208051-APC from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (Biotin) - 208051-Biotin from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (FITC) - 208051-FITC from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (HRP) - 208051-HRP from USBiological Life Science
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Anti -CCP4 (aa748-761) (AGBL1, ATP/GTP binding protein-like 1, FLJ32310, MGC149239,ATP/GTP-binding protein-like 1, OTTHUMP00000195714) (PE) - 208051-PE from USBiological Life Science
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Anti-AGBL1 Antibody - AC11-0378 from Abcore
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Anti-AGBL1 Antibody - AC21-2544 from Abcore
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Anti-AGBL1 Antibody (AMCA) - AC21-2544-01 from Abcore
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Anti-AGBL1 Antibody (AP) - AC21-2544-02 from Abcore
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Anti-AGBL1 Antibody (APC) - AC21-2544-03 from Abcore
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Anti-AGBL1 Antibody (APC-Cy5.5) - AC21-2544-04 from Abcore
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Anti-AGBL1 Antibody (APC-Cy7) - AC21-2544-05 from Abcore
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