Gene Symbol | AFM |
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Entrez Gene | 173 |
Alt Symbol | ALB2, ALBA, ALF |
Species | Human |
Gene Type | protein-coding |
Description | afamin |
Other Description | alpha-Alb|alpha-albumin |
Swissprots | A8K3E1 Q4W5C5 Q32MR3 P43652 |
Accessions | AAC50720 AAY41051 EAX05682 P43652 AK290556 BAF83245 BC109020 AAI09021 BC109021 AAI09022 L35486 AAA68197 L35497 AAA68198 L35498 AAA68199 NM_001133 NP_001124 |
Function | Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier. {ECO:0000269|PubMed:12463752, ECO:0000269|PubMed:15952736, ECO:0000269|PubMed:19046407}. |
Subcellular Location | Secreted. |
Tissue Specificity | High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). {ECO:0000269|PubMed:15952736}. |
Afamin CRISPR/Cas9 KO Plasmid (h) - sc-408109 from Santa Cruz Biotechnology
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Afamin HDR Plasmid (h) - sc-408109-HDR from Santa Cruz Biotechnology
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Afamin Double Nickase Plasmid (h) - sc-408109-NIC from Santa Cruz Biotechnology
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Afamin Double Nickase Plasmid (h2) - sc-408109-NIC-2 from Santa Cruz Biotechnology
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Afamin CRISPR Activation Plasmid (h) - sc-408109-ACT from Santa Cruz Biotechnology
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Afamin CRISPR Activation Plasmid (h2) - sc-408109-ACT-2 from Santa Cruz Biotechnology
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Afamin Lentiviral Activation Particles (h) - sc-408109-LAC from Santa Cruz Biotechnology
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Afamin Lentiviral Activation Particles (h2) - sc-408109-LAC-2 from Santa Cruz Biotechnology
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Afamin siRNA (h) - sc-72462 from Santa Cruz Biotechnology
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Afamin shRNA Plasmid (h) - sc-72462-SH from Santa Cruz Biotechnology
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Afamin shRNA (h) Lentiviral Particles - sc-72462-V from Santa Cruz Biotechnology
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Afamin RNAi - H00000173-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2921 from Sigma-Aldrich
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AFM siRNA (Human) - CRH0122 from Cohesion Biosciences
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AFM - MBS8231009 from MyBioSource
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shRNA set against Human AFM (NM_001133.2) - SHH233046 from Creative biogene
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shRNA set against Human AFM(NM_001133.2) - SHG030959 from Creative biogene
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Human AFM siRNA - orb260624 from Biorbyt
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AFM shRNA Plasmid (Human) - CHH0122 from Cohesion Biosciences
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AFM miRNA 3'UTR clone - MiUTR1H-00231 from Creative biogene
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