| Gene Symbol | TRAFD1 |
|---|---|
| Entrez Gene | 10906 |
| Alt Symbol | FLN29 |
| Species | Human |
| Gene Type | protein-coding |
| Description | TRAF-type zinc finger domain containing 1 |
| Other Description | FLN29 gene product|TRAF-type zinc finger domain-containing protein 1 |
| Swissprots | O14545 A8K5L6 B4DI89 |
| Accessions | CCQ43370 EAW97995 EAW97996 EAW97997 O14545 AB007447 BAA22541 AK122620 AK291331 BAF84020 AK295474 BAG58401 AK309916 AK312601 BC003553 AAH03553 BG828961 CA314188 DQ892530 ABM83456 DQ895741 ABM86667 NM_001143906 NP_001137378 NM_006700 NP_006691 |
| Function | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity). {ECO:0000250}. |
TRAF-type zinc finger domain containing 1, ELISA Kit - MBS9330403 from MyBioSource
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Human TRAFD1 ELISA Kit - E038716 from Biobool
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