Gene Symbol | TRAFD1 |
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Entrez Gene | 10906 |
Alt Symbol | FLN29 |
Species | Human |
Gene Type | protein-coding |
Description | TRAF-type zinc finger domain containing 1 |
Other Description | FLN29 gene product|TRAF-type zinc finger domain-containing protein 1 |
Swissprots | O14545 A8K5L6 B4DI89 |
Accessions | CCQ43370 EAW97995 EAW97996 EAW97997 O14545 AB007447 BAA22541 AK122620 AK291331 BAF84020 AK295474 BAG58401 AK309916 AK312601 BC003553 AAH03553 BG828961 CA314188 DQ892530 ABM83456 DQ895741 ABM86667 NM_001143906 NP_001137378 NM_006700 NP_006691 |
Function | Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity). {ECO:0000250}. |
TRAFD1 CRISPR/Cas9 KO Plasmid (h) - sc-407366 from Santa Cruz Biotechnology
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TRAFD1 HDR Plasmid (h) - sc-407366-HDR from Santa Cruz Biotechnology
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TRAFD1 Double Nickase Plasmid (h) - sc-407366-NIC from Santa Cruz Biotechnology
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TRAFD1 Double Nickase Plasmid (h2) - sc-407366-NIC-2 from Santa Cruz Biotechnology
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TRAFD1 CRISPR Activation Plasmid (h) - sc-407366-ACT from Santa Cruz Biotechnology
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TRAFD1 CRISPR Activation Plasmid (h2) - sc-407366-ACT-2 from Santa Cruz Biotechnology
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TRAFD1 Lentiviral Activation Particles (h) - sc-407366-LAC from Santa Cruz Biotechnology
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TRAFD1 Lentiviral Activation Particles (h2) - sc-407366-LAC-2 from Santa Cruz Biotechnology
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TRAFD1 siRNA (h) - sc-63145 from Santa Cruz Biotechnology
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TRAFD1 shRNA Plasmid (h) - sc-63145-SH from Santa Cruz Biotechnology
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TRAFD1 shRNA (h) Lentiviral Particles - sc-63145-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21912 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21912 from Sigma-Aldrich
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TRAFD1 siRNA (Human) - CRH7435 from Cohesion Biosciences
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TRAFD1 RNAi - H00010906-R01 from Novus Biologicals
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TRAFD1 - MBS8201195 from MyBioSource
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TRAFD1 CRISPR/Cas9 KO Plasmid (h2) - sc-407366-KO-2 from Santa Cruz Biotechnology
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TRAFD1 HDR Plasmid (h2) - sc-407366-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TRAFD1 (NM_006700.2) - SHH433796 from Creative biogene
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Human TRAFD1 siRNA - orb267937 from Biorbyt
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TRAFD1 shRNA Plasmid (Human) - CHH7435 from Cohesion Biosciences
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TRAFD1 miRNA 3'UTR clone - MiUTR3H-12777 from Creative biogene
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TRAFD1 miRNA 3'UTR clone - MiUTR3H-12778 from Creative biogene
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