LEPR

Gene Symbol	LEPR
Entrez Gene	3953
Alt Symbol	CD295, LEP-R, LEPRD, OB-R, OBR
Species	Human
Gene Type	protein-coding
Description	leptin receptor
Other Description	OB receptor|huB219
Swissprots	Q13592 Q13593 P48357 Q92921 Q92920 Q92919 Q13594
Accessions	AAB09673 AGB14642 CAH25983 P48357 AA813024 AI436180 AK001042 AK290208 BAF82897 AW302522 BC031086 AAH31086 BC035120 BC131779 AAI31780 BC160009 AAI60009 BX475249 U43168 AAA93015 U50748 AAC23650 U52912 AAC50509 U52913 AAC50510 U52914 AAC50511 U66495 AAB07495 U66496 AAB07496 U66497 AAB07497 NM_001003679 NP_001003679 NM_001003680 NP_001003680 NM_001198687 NP_001185616 NM_001198688 NP_001185617 NM_001198689 NP_001185618 NM_002303 NP_002294
Function	Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LeptinR (CD295) Human ELISA Kit - ab119574 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 8 pg/ml Range 156 pg/ml - 10000 pg/ml

Human LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F5118 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 14.1 pg/ml Range 312-20000 pg/ml

Mouse LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F5119 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 14.5 pg/ml Range 312-20000 pg/ml

Rat LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F5535 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.67 ng/ml Range 312-20000 pg/ml

Human LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F2943 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 20 pg/ml Range 312-20000 pg/ml

Mouse LEPR / Leptin Receptor ELISA Kit (Custom ELISA) - LS-F498 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity To be determined Range 312-20000 pg/ml

Mouse LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F10481 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 5 pg/ml Range 312-20000 pg/ml

Human LEPR / Leptin Receptor ELISA Kit (Sandwich ELISA) - LS-F11939 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.78 Range 312-20000 pg/ml

Human Leptin R Quantikine ELISA Kit - DOBR00 from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 0.128 ng/mL Range 0.3 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human Total Leptin R DuoSet IC ELISA, 2 Plate - DYC389-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 250.00 - 16,000 pg/mL

Mouse Leptin R DuoSet ELISA - DY497 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 31.20 - 2,000 pg/mL

Human Leptin R DuoSet ELISA - DY389 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 0.312 - 20 ng/mL

Quantikine Immunoassay Control Set 804 for Human Leptin R - QC112 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human Leptin Receptor ELISA kit - 55R-1637 from Fitzgerald Category ELISA Kit Prices $350.00 Sizes 1 kit

Mouse Leptin Receptor ELISA kit - 55R-1638 from Fitzgerald Category ELISA Kit Prices $415.00 Sizes 1 kit

Human Leptin Receptor ELISA Kit - orb219310 from Biorbyt Category ELISA Kit Prices $706.00 Sizes 96 test Sensitivity 10 pg/ml Range 156 pg/ml-10000 pg/ml

Human CD295 ELISA Kit - abx056096 from Abbexa Category ELISA Kit

Human Leptin Receptor ELISA Kit - abx052394 from Abbexa Category ELISA Kit

Human Leptin Receptor ELISA kit - abx050144 from Abbexa Category ELISA Kit Sensitivity < 8pg/ml Range 156 pg/ml-10, 000 pg/ml

Human Leptin Receptor ELISA Kit - abx152193 from Abbexa Category ELISA Kit Sensitivity 13.1 pg/ml Range 31.25 pg/ml - 2000 pg/ml

Human Leptin Receptor ELISA Kit - abx052393 from Abbexa Category ELISA Kit

Leptin Receptor, LEPR, Human, ELISA Kit - E-EL-H0093 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Leptin receptor, Human, ELISA Kit - PB-0439 from ARP American Research Products Category ELISA Kit Prices $369.00 Sizes 96 t Sensitivity < 8 pg/ml Range 156pg/ml-10,000pg/ml

Leptin receptor, Human, ELISA Kit - E01L0273 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Leptin receptor, LR/Ob-R, Human, ELISA Kit - CSB-E04647h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.78 pg/ml Range 3.12 pg/ml-200 pg/ml

Search more