CENPU

Gene Symbol	CENPU
Entrez Gene	79682
Alt Symbol	CENP50, CENPU50, KLIP1, MLF1IP, PBIP1
Species	Human
Gene Type	protein-coding
Description	centromere protein U
Other Description	KSHV latent nuclear antigen interacting protein 1|KSHV latent nuclear antigen-interacting protein 1|MLF1 interacting protein|MLF1-interacting protein|centromere protein of 50 kDa|interphase centromere complex protein 24|polo-box-interacting protein 1
Swissprots	Q32Q71 A2RRD9 Q71F23 Q9H5G1 Q09GN2
Accessions	EAX04666 Q71F23 AA761728 AF469667 AAQ05290 AF516710 AAQ08228 AK027121 BAB15665 AK292297 BAF84986 AW440254 BC031520 AAH31520 BC067802 BC107744 AAI07745 BC131556 AAI31557 BC141854 AAI41855 BG031878 BX355581 CR457376 CAG33657 DQ907910 ABI49142 DQ907911 ABI49143 XM_005263218 XP_005263275 NM_024629 NP_078905 NR_104593
Function	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression. {ECO:0000269|PubMed:12941884, ECO:0000269|PubMed:16716197, ECO:0000269|PubMed:17081991}.
Subcellular Location	Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Note=Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates.
Tissue Specificity	Expressed at high levels in the testis, fetal liver, thymus, bone marrow and at lower levels in the lymph nodes, placenta, colon and spleen. Present in all cell lines examined, including B-cells, T-cells, epithelial cells and fibroblast cells. Expressed at high levels in glioblastoma cell lines. {ECO:0000269|PubMed:12941884, ECO:0000269|PubMed:15116101, ECO:0000269|PubMed:15893739}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MLF1 Interacting Protein/PBIP1 full length protein - ab164074 from Abcam Category Protein Source Wheat germ Species Human

Human MLF1 Interacting Protein/PBIP1 protein fragment - ab174458 from Abcam Category Protein Source E. coli Species Human

CENPU / MLF1IP Antibody Blocking Peptide - LS-E5026 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CENPU / MLF1IP Antibody Blocking Peptide - LS-E21734 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CENPU / MLF1IP Antibody Blocking Peptide - LS-E21735 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MLF1 Interacting Protein Recombinant Protein - H00079682-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human MLF1 Interacting Protein Protein - NBP2-23247 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

MLF1IP-Antibody-C-term-Blocking-Peptide - BP17429b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MLF1IP protein (His tag) - 80R-3628 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

MLF1IP (147-418, His-tag) - AR51315PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

MLF1IP (147-418, His-tag) - AR51315PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

MLF1IP - H00079682-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MLF1IP - H00079682-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MLF1IP, 147-418a, Human, His tag, E.coli - 01-P2495 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

MLF1IP fusion protein - ag15271 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MLF1IP fusion protein - Ag3858 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant human MLF1IP, His-tagged - MLF1IP-2495H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human MLF1IP - MLF1IP-1060H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Centromere protein U(MLF1IP) - CSB-YP744481HU CSB-EP744481HU CSB-BP744481HU CSB-MP744481HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MLF1IP, 147-418a, Human, His tag, E.coli (Denatured) - ATGP2495 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Centromere protein U (MLF1IP), Recombinant Protein - MBS1364641 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,920.00, $1,920.00, $2,385.00, $2,385.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Centromere Protein-U, Recombinant Protein - MBS146164 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

Human CENPU protein - orb259838 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

MLF1 Interacting Protein Recombinant Protein Antigen - NBP1-85689PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MLF1IP Peptide, Human - M34GP09557H from Creative Peptides Category Peptide Source Synthetic. Species Human

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