CASK

Gene Symbol	CASK
Entrez Gene	8573
Alt Symbol	CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8
Species	Human
Gene Type	protein-coding
Description	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Other Description	calcium/calmodulin-dependent serin protein kinase|calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase|hCASK|peripheral plasma membrane protein CASK|protein lin-2 homolog|trinucleotide repeat containing 8
Swissprots	Q9BYH6 Q9NYB3 Q66T42 Q5VT18 B7ZKY0 Q9NYB2 Q5VT16 Q59HA0 O43215 Q5VT19 A6NES1 Q5VT17 O14936 Q17RI4
Accessions	EAW59390 EAW59391 EAW59392 EAW59393 O14936 AB039327 BAB12252 AB208859 BAD92096 AF032119 AAB88125 AF035582 AAB88198 AF262404 AAF72666 AF262405 AAF72667 AK025872 AK056476 AK313399 AY705392 AAU10527 BC029936 BC035990 BC117311 AAI17312 BC143454 AAI43455 BC143456 AAI43457 DN993605 HQ258518 ADR83272 LN607837 CEF49524 XM_005272686 XP_005272743 XM_006724566 XP_006724629 XM_011543993 XP_011542295 XM_011543994 XP_011542296 XM_011543995 XP_011542297 XM_011543996 XP_011542298 XM_011543997 XP_011542299 NM_001126054 NP_001119526 NM_001126055 NP_001119527 NM_003688 NP_003679
Function	Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver. {ECO:0000269|PubMed:11003712}.
Top Pathways	Tight junction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CASK protein fragment - ab131707 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

CASK peptide - ab4961 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

Human CASK full length protein - ab199574 from Abcam Category Protein Prices $429.00 Sizes 10 µg Source HEK 293 cells Species Human

CASK Antibody Blocking Peptide - LS-E8770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CASK Antibody Blocking Peptide - LS-E31293 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CASK Peptide - P2381 from Novus Biologicals Category Peptide Species Human

Mouse-Cask-Antibody-N-term-Blocking-Peptide - BP14818a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg Species Mouse

CASK-Antibody-Center-K227-Blocking-peptide - BP7212c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cask-Antibody-C-term-Blocking-Peptide - BP7212a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human CASK protein - orb138312 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source Baculovirus-Insect Cells Species Human

Human CASK His GST tag protein - orb84293 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 20 μg, 50 μg Source Insect Species Human

CASK (N-term) Control Peptide - AP55443CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CASK Control Peptide - SP5225CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

CASK Peptide - 6921P from ProSci Category Peptide Species Human

Recombinant Human CASK, His & GST tagged - CASK-3940H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human CASK, Gly & Pro tagged - CASK-465H from Creative Biomart Category Protein Source Baculovirus-Insect cells Species Human

Recombinant Human CASK (Active), GST-tagged - CASK-1375H from Creative Biomart Category Protein Source Sf9 Cells Species Human

CASK - PN201409 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Baculovirus Species Human

Human CASK Kinase Protein - 11913-HNCB-20 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Human CASK Kinase Protein (His & GST Tag) - 11913-H20B-20 from Sino Biological Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human Peripheral plasma membrane protein CASK(CASK) ,partial - CSB-YP004539HU CSB-EP004539HU CSB-BP004539HU CSB-MP004539HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CASK (353-459) - sc-4514 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

CASK (transcript variant 1) - TP320531 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Peripheral plasma membrane protein CASK (CASK), partial, Recombinant Protein - MBS1233735 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human CASK Kinase Protein - PKSH030972 from Elabscience Category Protein Source Baculoviru Species Human

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