NKX2-5

Gene Symbol NKX2-5
Entrez Gene 1482
Alt Symbol CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3
Species Human
Gene Type protein-coding
Description NK2 homeobox 5
Other Description NK2 transcription factor related, locus 5|cardiac-specific homeobox 1|homeobox protein CSX|homeobox protein NK-2 homolog E|homeobox protein Nkx-2.5|tinman paralog
Swissprots P52952 E9PBU6 B4DNB6 A8K3K0
Accessions ABL63553 ABL63554 ABL63555 ABL63556 ABL63557 ABL63558 ABL63559 ABL63560 ABL63561 ABL63562 ABL63563 ABL63564 ABL63565 ABL63566 ABL63567 ABL63568 ABL63569 ABL63570 ABL63571 ABL63572 ABL63573 ABL63574 ABL63575 ABL63576 ABL63577 ABL63578 ABL63579 ABL63580 ABL63581 ABL63582 ABL63583 ABL63584 ABL63585 ABL63586 ABL63587 ABL63588 ABL63589 ABL63590 ABL63591 ABL63592 ABL63593 ABL63594 ABL63595 ABL63596 ABL63597 ABL63598 ABL63599 ABL63600 ABL63601 ABL63602 ABL63603 ABL63604 ABL63605 ABL63606 ABL63607 ABL63608 ABL63609 ABL63610 ABL63611 ABL63612 ABL63613 ABL63614 ABL63615 ABL63616 ABL63617 ABL63618 ABL63619 ABL63620 ABL63621 ABL63622 ABL63623 ABL63624 ABL63625 ABL63626 ABL63627 ABL63628 ABL63629 ABL63630 ABL63631 ABL63632 ABL63633 ABL63634 ABL63635 ABL63636 EAW61404 P52952 AB021133 BAA35181 AI609745 AK290615 BAF83304 AK297844 BAG60178 AK307218 AK307247 AK307249 AK309495 BC025711 AAH25711 DA559427 DQ893313 ABM84239 DQ894104 ABM85030 DQ896627 ABM87626 U34962 AAC50470 NM_001166175 NP_001159647 NM_001166176 NP_001159648 NM_004387 NP_004378
Function Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development. {ECO:0000250, ECO:0000269|PubMed:22560297}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed only in the heart.

NKX2.5 (E1Y8H) Rabbit mAb - 8792 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone E1Y8H
Western blot analysis of extracts from various cell lines using NKX2.5 (E1Y8H) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

NKX2.5 Antibody - 5444 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Nkx-2.5 (A-3) - sc-376565 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nkx-2.5 (A-3): sc-376565. Western blot analysis of Nkx-2.5 expression in non-transfected: sc-117752 (A) and human Nkx-2.5 transfected: sc-114181 (B) 293T whole cell lysates.

Nkx-2.5 (F-2) - sc-365207 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nkx-2.5 (F-2): sc-365207. Western blot analysis of Nkx-2.5 expression in non-transfected: sc-117752 (A) and human Nkx-2.5 transfected: sc-114181 (B) 293T whole cell lysates.

Nkx-2.5 (H-114) - sc-14033 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Nkx-2.5 (H-114): sc-14033. Western blot analysis of Nkx-2.5 expression in non-transfected: sc-117752 (A) and human Nkx-2.5 transfected: sc-114181 (B) 293T whole cell lysates.

Nkx-2.5 (N-19) - sc-8697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nkx-2.5 (N-19): sc-8697. Immunofluorescence staining of methanol-fixed A549 cells showing nuclear and cytoplasmic localization.

Nkx-2.5 (A-16) - sc-12514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nkx-2.5 (A-16): sc-12514. Western blot analysis of Nkx-2.5 expression in non-transfected: sc-117752 (A) and human Nkx-2.5 transfected: sc-114181 (B) 293T whole cell lysates.

Anti-Nkx2.5 antibody - ab35842 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Nkx2.5 antibody (ab35842) at 1 µg/ml + Full length human recombinant Nkx2.5 at 0.4 µgSecondaryRabbit IgG secondary antibody (ab28446) at 1/10000 dilution

Anti-Nkx2.5 antibody - ab22611 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Nkx2.5 antibody (ab22611) at 1 µg/ml + Full length recombinant Nkx2.5 with GST tag at 0.4 µgSecondaryRabbit IgG secondary antibody (ab28446) at 1/10000 dilution

Anti-Nkx2.5 antibody - ab106923 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Nkx2.5 antibody (ab106923) at 0.3 µg/ml + Human heart lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-Nkx2.5 antibody - ab173204 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Nkx2.5 antibody (ab173204) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

Anti-Nkx2.5 antibody - ab54567 from Abcam

Host Mouse
Clonality Monoclonal

Anti-Nkx2.5 antibody - ab187114 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-Nkx2.5 antibody (ab187114) at 1/1000 dilution + HeLa total cell extract

Anti-Nkx2.5 antibody [2E1] - ab91196 from Abcam

Prices $387.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E1
Anti-Nkx2.5 antibody [2E1] (ab91196) at 1/500 dilution + cell lysate from HEK293 cells transfected with full-length Nkx2.5 (aa 1-324) linked to hIgGFc

Anti-Nkx2.5 antibody [MM0839-5Z56] - ab201654 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0839-5Z56

Anti-NKX2-5 Antibody (Ala71) - LS-C191098 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (aa82-111, AP) - LS-C264440 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (aa82-111, APC) - LS-C264443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (aa82-111, Biotin) - LS-C264444 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (aa82-111, FITC) - LS-C264445 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (clone 2E1) - LS-C109107 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E1
Western blot using NKX2.5 mouse monoclonal antibody against full-length NKX2.5 (aa1-324)-hIgGFc transfected HEK293 cell lysate (1).

Anti-NKX2-5 Antibody (N-Terminus) - LS-C110205 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NKX2-5 antibody LS-C110205 Western blot of Mouse Thymus lysate.

Anti-NKX2-5 Antibody (aa82-111, Azide-free, HRP) - LS-C264446 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKX2-5 Antibody (aa72-121) - LS-C109603 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NKX2-5 antibody LS-C109603 Western blot of MCF7 cell lysate.

Anti-NKX2-5 Antibody (aa82-111, PE) - LS-C264448 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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