NKX2-5

Gene Symbol	NKX2-5
Entrez Gene	1482
Alt Symbol	CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3
Species	Human
Gene Type	protein-coding
Description	NK2 homeobox 5
Other Description	NK2 transcription factor related, locus 5|cardiac-specific homeobox 1|homeobox protein CSX|homeobox protein NK-2 homolog E|homeobox protein Nkx-2.5|tinman paralog
Swissprots	P52952 E9PBU6 B4DNB6 A8K3K0
Accessions	ABL63553 ABL63554 ABL63555 ABL63556 ABL63557 ABL63558 ABL63559 ABL63560 ABL63561 ABL63562 ABL63563 ABL63564 ABL63565 ABL63566 ABL63567 ABL63568 ABL63569 ABL63570 ABL63571 ABL63572 ABL63573 ABL63574 ABL63575 ABL63576 ABL63577 ABL63578 ABL63579 ABL63580 ABL63581 ABL63582 ABL63583 ABL63584 ABL63585 ABL63586 ABL63587 ABL63588 ABL63589 ABL63590 ABL63591 ABL63592 ABL63593 ABL63594 ABL63595 ABL63596 ABL63597 ABL63598 ABL63599 ABL63600 ABL63601 ABL63602 ABL63603 ABL63604 ABL63605 ABL63606 ABL63607 ABL63608 ABL63609 ABL63610 ABL63611 ABL63612 ABL63613 ABL63614 ABL63615 ABL63616 ABL63617 ABL63618 ABL63619 ABL63620 ABL63621 ABL63622 ABL63623 ABL63624 ABL63625 ABL63626 ABL63627 ABL63628 ABL63629 ABL63630 ABL63631 ABL63632 ABL63633 ABL63634 ABL63635 ABL63636 EAW61404 P52952 AB021133 BAA35181 AI609745 AK290615 BAF83304 AK297844 BAG60178 AK307218 AK307247 AK307249 AK309495 BC025711 AAH25711 DA559427 DQ893313 ABM84239 DQ894104 ABM85030 DQ896627 ABM87626 U34962 AAC50470 NM_001166175 NP_001159647 NM_001166176 NP_001159648 NM_004387 NP_004378
Function	Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development. {ECO:0000250, ECO:0000269|PubMed:22560297}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed only in the heart.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nkx2.5 full length protein - ab152305 from Abcam Category Protein Source Wheat germ Species Human

Human Nkx2.5 peptide - ab25302 from Abcam Category Peptide

Human Nkx2.5 peptide - ab25303 from Abcam Category Peptide

NKX2-5 Antibody Blocking Peptide - LS-E5005 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-5 Antibody Blocking Peptide - LS-E13248 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-5 Antibody Blocking Peptide - LS-E11036 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKX2-5 Antibody Blocking Peptide - LS-E27080 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NKX2.5 Protein - H00001482-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

NKX2-5-Antibody-Center-Blocking-Peptide - BP17406c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

nkx2.5 Peptide - AC21-1902-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NKX2-5 - H00001482-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NKX2-5 - H00001482-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

NKX2-5 - H00001482-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

CSX1 Peptide - 42-012P from ProSci Category Peptide Species Human, Mouse, Rat

NKX2-5 fusion protein - ag4930 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NKX2-5 fusion protein - ag5534 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Homeobox protein Nkx-2.5(NKX2-5) - CSB-YP015845HU CSB-EP015845HU CSB-BP015845HU CSB-MP015845HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NKX2-5 - TP306550 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CSX1/NKX2-5, Peptide - MBS426485 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine, Dog

NKX2-5 Peptide, Human - M34GP10413H from Creative Peptides Category Peptide Source Synthetic. Species Human

NKX2-5 Antibody - SH-A14032 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

Recombinant Human NK2 Homeobox 5 - 230-00848-10 from RayBiotech Category Protein Source Escherichia coli (E.coli) Species Human

Homeobox protein Nkx-2.5 (NKX2-5), Recombinant Protein - MBS960223 from MyBioSource Category Protein Prices $1,085.00, $1,085.00, $1,315.00, $1,315.00, $1,705.00, $1,705.00, $2,170.00, $2,170.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

NKX2.5 Recombinant Protein Antigen - NBP2-57744PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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