Gene Symbol | PLAUR |
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Entrez Gene | 5329 |
Alt Symbol | CD87, U-PAR, UPAR, URKR |
Species | Human |
Gene Type | protein-coding |
Description | plasminogen activator, urokinase receptor |
Other Description | monocyte activation antigen Mo3|u-plasminogen activator receptor form 2|urokinase plasminogen activator surface receptor|urokinase-type plasminogen activator (uPA) receptor |
Swissprots | Q9UMV0 Q6IB52 Q12876 A8K409 Q9UM92 Q16887 Q9UEA6 Q03405 Q9UD69 Q15845 Q9BWT0 Q9NYC8 |
Accessions | AAA17979 AAB60690 AAC32739 AAD14289 AAD17387 AAD17388 AAD17389 AAN86351 AAT52166 AAT52167 AAT52168 CAO02271 EAW57215 EAW57216 EAW57217 EAW57218 EAW57219 EAW57220 Q03405 A18757 CAA01421 AA337688 AA643630 AF257789 AAF71751 AI801128 AI912302 AK290774 BAF83463 AY029180 AAK31795 BC002788 AAH02788 BY996586 CA495321 CD370232 CF126152 CR456952 CAG33233 DQ893017 ABM83943 DQ896262 ABM87261 M83246 AAA59862 U08839 AAB60333 U09347 AAA17978 X51675 CAA35981 X74039 CAA52191 XM_005258990 XP_005259047 XM_011527027 XP_011525329 XM_011527028 XP_011525330 XM_011527029 XP_011525331 XM_011527030 XP_011525332 XM_011527031 XP_011525333 NM_001005376 NP_001005376 NM_001005377 NP_001005377 NM_001301037 NP_001287966 NM_002659 NP_002650 |
Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
Subcellular Location | Isoform 2: Secreted {ECO:0000305}. |
Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
Top Pathways | Complement and coagulation cascades, Proteoglycans in cancer |
Active human uPA Receptor protein fragment - ab191662 from Abcam
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Human uPA Receptor protein fragment - ab151815 from Abcam
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Recombinant Mouse uPAR Fc Chimera, CF - 531-PA-100 from R&D Systems
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Recombinant Human uPAR - 807-UK-100 from R&D Systems
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Recombinant Human uPAR, CF - 807-UK-100/CF from R&D Systems
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Recombinant rat Urokinase plasminogen activator surface receptor (OPCA00185) - OPCA00185 from Aviva Systems Biology
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Human CD87 protein - orb83099 from Biorbyt
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Human PLAUR protein - orb246409 from Biorbyt
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Human uPAR His tag protein - orb84460 from Biorbyt
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Human uPAR protein - orb49724 from Biorbyt
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uPAR Blocking Peptide - 33R-10906 from Fitzgerald
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Human uPAR Protein - abx068569 from Abbexa
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Human uPAR Protein - abx068572 from Abbexa
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Human uPAR Protein - abx068573 from Abbexa
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Plasminogen Activator, Urokinase Receptor (uPAR), Human - 20-6330 from ARP American Research Products
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Plasminogen Activator, Urokinase Receptor (uPAR), Human - 20-6331 from ARP American Research Products
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Plasminogen Activator, Urokinase Receptor (uPAR), Human - 20-6332 from ARP American Research Products
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Urokinase Plasminogen Activator Surface Receptor, uPAR, Human, Recombinant - 19-C382 from ARP American Research Products
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CD87 Recombinant Protein - 96-763 from ProSci
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uPAR, PLAUR fusion protein - ag0187 from Proteintech Group
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Recombinant Human uPAR Protein - BP001710-C382 from Syd Labs
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Recombinant Human Plasminogen Activator, Urokinase Receptor - PLAUR-1513H from Creative Biomart
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Recombinant Human PLAUR, His tagged - PLAUR-3861H from Creative Biomart
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Recombinant Human Plasminogen Activator, Urokinase Receptor - PLAUR-412H from Creative Biomart
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Recombinant Plasminogen Activator, Urokinase Receptor (uPAR) - RPA141Hu01 from Uscn Life Science Inc.
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