PLAUR

Gene Symbol PLAUR
Entrez Gene 5329
Alt Symbol CD87, U-PAR, UPAR, URKR
Species Human
Gene Type protein-coding
Description plasminogen activator, urokinase receptor
Other Description monocyte activation antigen Mo3|u-plasminogen activator receptor form 2|urokinase plasminogen activator surface receptor|urokinase-type plasminogen activator (uPA) receptor
Swissprots Q9UMV0 Q6IB52 Q12876 A8K409 Q9UM92 Q16887 Q9UEA6 Q03405 Q9UD69 Q15845 Q9BWT0 Q9NYC8
Accessions AAA17979 AAB60690 AAC32739 AAD14289 AAD17387 AAD17388 AAD17389 AAN86351 AAT52166 AAT52167 AAT52168 CAO02271 EAW57215 EAW57216 EAW57217 EAW57218 EAW57219 EAW57220 Q03405 A18757 CAA01421 AA337688 AA643630 AF257789 AAF71751 AI801128 AI912302 AK290774 BAF83463 AY029180 AAK31795 BC002788 AAH02788 BY996586 CA495321 CD370232 CF126152 CR456952 CAG33233 DQ893017 ABM83943 DQ896262 ABM87261 M83246 AAA59862 U08839 AAB60333 U09347 AAA17978 X51675 CAA35981 X74039 CAA52191 XM_005258990 XP_005259047 XM_011527027 XP_011525329 XM_011527028 XP_011525330 XM_011527029 XP_011525331 XM_011527030 XP_011525332 XM_011527031 XP_011525333 NM_001005376 NP_001005376 NM_001005377 NP_001005377 NM_001301037 NP_001287966 NM_002659 NP_002650
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Subcellular Location Isoform 2: Secreted {ECO:0000305}.
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Top Pathways Complement and coagulation cascades, Proteoglycans in cancer

uPAR Antibody - 9692 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from U-937 cells, pre-incubated with TPA #4174 (200 nM, 72 hr) and either left untreated (-) or treated (+) with PNGaseF, using uPAR Antibody.

uPAR (D4Q5S) Rabbit mAb - 12863 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4Q5S
Western blot analysis of extracts from U-937 cells, untreated (-) or treated with TPA #4174 (200 nM, 72 hr; +), using uPAR (D4Q5S) Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

uPAR (D7X2N) Rabbit mAb - 12713 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7X2N
Western blot analysis of extracts from U-937 cells, untreated (-) or treated (+) with TPA #4174 (200 nM, 72 hr), using uPAR (D7X2N) Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

uPAR (E-3) - sc-376494 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
uPAR (E-3): sc-376494. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells and staining of plasma in blood vessels.

uPAR (FL-290) - sc-10815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
uPAR (FL-290): sc-10815. Western blot analysis of uPAR expression in HeLa whole cell lysate.

uPAR (D-5) - sc-376118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
uPAR (D-5): sc-376118. Western blot analysis of uPAR expression in non-transfected: sc-117752 (A) and human uPAR transfected: sc-159642 (B) 293T whole cell lysates.

uPAR (N-19) - sc-9793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
uPAR (N-19): sc-9793. Western blot analysis of human recombinant uPAR.

uPAR (10G7) - sc-13522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
uPAR (10G7): sc-13522. Western blot analysis of human recombinant uPAR.

uPAR (C-16) - sc-9791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
uPAR (C-16): sc-9791. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tumor showing membrane and cytoplasmic staining.

Anti-uPA Receptor antibody - ab103791 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-uPA Receptor antibody (ab103791) at 1 µg/mlLane 1 : Human placenta tissue lysateLane 2 : Rat brain tissue lysateLane 3 : Rat thymus tissue lysateLane 4 : Rat heart tissue lysateLane 5 : MCF7 whole cell lysateLane 6 : SMMC whole cell lysateLane 7 : HeLa whole cell lysateLane 8 : Raji whole cell lysateLane 9 : Colo320 whole cell lysate

Anti-uPA Receptor antibody - ab3129 from Abcam

Host Goat
Clonality Polyclonal

Anti-uPA Receptor antibody - ab52327 from Abcam

Host Goat
Clonality Polyclonal

Anti-uPA Receptor antibody [MM0597-18L1] - ab89932 from Abcam

Host Mouse
Clonality Monoclonal
Clone MM0597-18L1

Anti-uPA Receptor antibody [R-4] - ab82220 from Abcam

Host Mouse
Clonality Monoclonal
Clone R-4
Overlay histogram showing SH-SY5Y cells stained with ab82220 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab82220, 2µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.

uPAR Antibody - AF807 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

uPAR Antibody - NBP2-14711 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: uPAR Antibody [NBP2-14711] - uPA Receptor Antibody Staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.

uPAR Antibody [Biotin] - BAF807 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

uPAR Antibody (62022) [Phycoerythrin] - FAB807P from Novus Biologicals

Prices $309.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 62022
Human peripheral blood granulocytes were stained with Mouse Anti-Human uPAR PE-conjugated Monoclonal Antibody (Catalog # FAB807P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

PLAUR Polyclonal Antibody - bs-1927R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-PLAUR Polyclonal Antibody, Unconjugated (bs-1927R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-PLAUR antibody produced in rabbit - SAB2700745 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLAUR: <B>Cat. No. SAB2700745</B>: Western Blot analysis of PLAUR in extracts from <B>Lanes</B><BR/>A. 293T <BR/>B. A431 using <B>Cat. No. SAB2700745</B> at a 1:1000 dilution.

Anti-PLAUR antibody produced in rabbit - SAB4200358 from Sigma-Aldrich

Prices $342.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>HeLa cells were fixed and permeabilized with 4% paraformaldehyde followed by 0.5% Triton<SUP>™</SUP> X-100. Fixed cells were stained with 1 μg/mL Rabbit Anti-PLAUR (<B>Cat. No. SAB4200358</B>). The antibody was developed using Goat Anti-Rabbit IgG, Atto488 conjugate (<B>Cat. No. 18772</B>).

ANTI-PLAUR (CENTER) antibody produced in rabbit - SAB1301615 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLAUR (Center): <B>Cat. No. SAB1301615</B>: Western blot analysis of PLAUR (arrow) using rabbit polyclonal PLAUR Antibody (W151) HEK_293 cell lysates (2 μg/lane).<BR/><B>Lanes:</B><BR/>1. Nontransfected with the PLAUR gene<BR/>2. Transiently transfected with the PLAUR gene

Monoclonal Anti-PLAUR/uPAR antibody produced in mouse - SAB4200412 from Sigma-Aldrich

Prices $337.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone PL231
<B>Immunofluorescence</B><BR/>HEK-293T cells overexpressing human PLAUR were fixed and permeabilized with cold methanol followed by acetone. Fixed cells were stained with 10 μg/mL Mouse Anti-PLAUR (<B>Cat. No. SAB4200412</B>).The antibody was developed using Goat Anti-Mouse IgG, Cy3 conjugate. Cells were counterstained with DAPI (blue) to stain nuclei.

Anti-PLAUR antibody produced in rabbit - HPA050843 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLAUR:<B>Cat. No. HPA050843</B>: Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.

PLAUR Antibody - N-terminal region (ARP63076_P050) - ARP63076_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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