Gene Symbol | ATAD3B |
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Entrez Gene | 83858 |
Alt Symbol | AAA-TOB3, TOB3 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 3B |
Other Description | AAA-ATPase TOB3|ATPase family AAA domain-containing protein 3B |
Swissprots | Q9BUK4 A8K3H1 Q9ULE7 Q6ZRB5 Q5T9A4 |
Accessions | EAW56192 EAW56193 EAW56194 Q5T9A4 AB033099 BAA86587 AF343078 AAK38647 AK024028 BAB14787 AK097309 AK127857 AK128357 AK290586 BAF83275 AL834179 CAD38876 BC002542 AAH02542 BC009938 BC018701 AAH18701 BQ954571 XM_005244806 XP_005244863 XM_005244808 XP_005244865 XM_011542240 XP_011540542 XM_011542241 XP_011540543 XM_011542242 XP_011540544 XM_011542243 XP_011540545 XM_011542244 XP_011540546 XR_241045 XR_946776 NM_031921 NP_114127 |
Function | May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. {ECO:0000269|PubMed:22664726}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}; Peripheral membrane protein {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}. Note=Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A. {ECO:0000269|PubMed:22453275}. |
Tissue Specificity | Tends to be down-regulated in differentiated cells and re-expressed in pluripotent stem cells or cancer cells (at protein level). {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:22664726}. |
ATAD3B (C-13) - sc-104095 from Santa Cruz Biotechnology
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ATAD3B (D-14) - sc-104096 from Santa Cruz Biotechnology
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Anti-ATAD3B antibody - ab112563 from Abcam
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Anti-ATAD3B antibody - ab68064 from Abcam
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Anti-ATAD3B Antibody - LS-C306421 from LifeSpan Bioscience
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Anti-ATAD3B Antibody (C-Terminus) - LS-C144388 from LifeSpan Bioscience
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ATAD3B Antibody - NBP2-32409 from Novus Biologicals
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ATAD3B Antibody - H00083858-B01 from Novus Biologicals
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ATAD3B Antibody - H00083858-B01P from Novus Biologicals
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ATAD3B Antibody - NBP1-76587 from Novus Biologicals
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Anti-ATAD3B antibody produced in mouse - SAB1400727 from Sigma-Aldrich
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Anti-ATAD3B antibody produced in rabbit - SAB3500669 from Sigma-Aldrich
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Anti -ATAD3B (ATPase Family AAA Domain-containing Protein 3B, AAA-TOB3, KIAA1273, TOB3) - 123661 from USBiological Life Science
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Anti -ATAD3B (ATPase Family AAA Domain-containing Protein 3B, AAA-TOB3, KIAA1273, TOB3) - 146863 from USBiological Life Science
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ATAD3B antibody - orb75628 from Biorbyt
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ATAD3B (C-term) antibody - AP26156PU-N from Acris Antibodies
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ATAD3B antibody - H00083858-B01 from Acris Antibodies
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ATAD3B antibody - H00083858-B01P from Acris Antibodies
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ATAD3B Antibody - 6389 from ProSci
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ATAD3B antibody - 16610-1-AP from Proteintech Group
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ATAD3B Antibody - 254486 from ABBIOTEC
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ATAD3B Antibody - 25322 from Signalway Antibody
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ATAD3B, Polyclonal Antibody - MBS150279 from MyBioSource
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ATAD3B, Polyclonal Antibody - MBS2521944 from MyBioSource
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ATAD3B Antibody - EPP10640 from Elabscience
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