Gene Symbol | ATAD3B |
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Entrez Gene | 83858 |
Alt Symbol | AAA-TOB3, TOB3 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 3B |
Other Description | AAA-ATPase TOB3|ATPase family AAA domain-containing protein 3B |
Swissprots | Q9BUK4 A8K3H1 Q9ULE7 Q6ZRB5 Q5T9A4 |
Accessions | EAW56192 EAW56193 EAW56194 Q5T9A4 AB033099 BAA86587 AF343078 AAK38647 AK024028 BAB14787 AK097309 AK127857 AK128357 AK290586 BAF83275 AL834179 CAD38876 BC002542 AAH02542 BC009938 BC018701 AAH18701 BQ954571 XM_005244806 XP_005244863 XM_005244808 XP_005244865 XM_011542240 XP_011540542 XM_011542241 XP_011540543 XM_011542242 XP_011540544 XM_011542243 XP_011540545 XM_011542244 XP_011540546 XR_241045 XR_946776 NM_031921 NP_114127 |
Function | May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. {ECO:0000269|PubMed:22664726}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}; Peripheral membrane protein {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}. Note=Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A. {ECO:0000269|PubMed:22453275}. |
Tissue Specificity | Tends to be down-regulated in differentiated cells and re-expressed in pluripotent stem cells or cancer cells (at protein level). {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:22664726}. |
Human ATAD3B full length protein - ab164451 from Abcam
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ATAD3B Antibody Blocking Peptide - LS-E31134 from LifeSpan Bioscience
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Recombinant Human ATAD3B Protein - H00083858-P01 from Novus Biologicals
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ATAD3B Blocking Peptide - NBP1-76587PEP from Novus Biologicals
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ATAD3B - H00083858-P01-10 from Acris Antibodies
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ATAD3B - H00083858-P01-25 from Acris Antibodies
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ATAD3B control peptide - AP26156CP-N from Acris Antibodies
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ATAD3B Peptide - 6389P from ProSci
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ATAD3B fusion protein - ag9836 from Proteintech Group
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Recombinant Human ATAD3B, GST-tagged - ATAD3B-9955H from Creative Biomart
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Recombinant Human ATPase family AAA domain-containing protein 3B(ATAD3B) - CSB-YP713133HU CSB-EP713133HU CSB-BP713133HU CSB-MP713133HU from Cusabio
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ATAD3B Protein - abx163174 from Abbexa
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ATPase family AAA domain-containing protein 3B(ATAD3B) , Recombinant Protein - MBS1280191 from MyBioSource
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ATAD3B Recombinant Protein Antigen - NBP2-32409PEP from Novus Biologicals
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ATAD3B Peptide, Human - M34GP01077H from Creative Peptides
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