ATAD3B

Gene Symbol ATAD3B
Entrez Gene 83858
Alt Symbol AAA-TOB3, TOB3
Species Human
Gene Type protein-coding
Description ATPase family, AAA domain containing 3B
Other Description AAA-ATPase TOB3|ATPase family AAA domain-containing protein 3B
Swissprots Q9BUK4 A8K3H1 Q9ULE7 Q6ZRB5 Q5T9A4
Accessions EAW56192 EAW56193 EAW56194 Q5T9A4 AB033099 BAA86587 AF343078 AAK38647 AK024028 BAB14787 AK097309 AK127857 AK128357 AK290586 BAF83275 AL834179 CAD38876 BC002542 AAH02542 BC009938 BC018701 AAH18701 BQ954571 XM_005244806 XP_005244863 XM_005244808 XP_005244865 XM_011542240 XP_011540542 XM_011542241 XP_011540543 XM_011542242 XP_011540544 XM_011542243 XP_011540545 XM_011542244 XP_011540546 XR_241045 XR_946776 NM_031921 NP_114127
Function May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. {ECO:0000269|PubMed:22664726}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}; Peripheral membrane protein {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:18063578}. Note=Has been found to co-purify with nucleoids (PubMed:22453275). Since it does not face the mitochondrial matrix, the association with nucleoids could be mediated by ATAD3A. {ECO:0000269|PubMed:22453275}.
Tissue Specificity Tends to be down-regulated in differentiated cells and re-expressed in pluripotent stem cells or cancer cells (at protein level). {ECO:0000269|PubMed:16909202, ECO:0000269|PubMed:22664726}.

ATAD3B CRISPR/Cas9 KO Plasmid (h) - sc-405547 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B HDR Plasmid (h) - sc-405547-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B Double Nickase Plasmid (h) - sc-405547-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B Double Nickase Plasmid (h2) - sc-405547-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B CRISPR Activation Plasmid (h) - sc-405547-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B CRISPR Activation Plasmid (h2) - sc-405547-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B Lentiviral Activation Particles (h) - sc-405547-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B Lentiviral Activation Particles (h2) - sc-405547-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATAD3B siRNA (h) - sc-88670 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATAD3B shRNA Plasmid (h) - sc-88670-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATAD3B shRNA (h) Lentiviral Particles - sc-88670-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU128081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3627 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3627 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12075 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12075

ATAD3B siRNA (Human) - CRJ3208 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATAD3B RNAi - H00083858-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ATAD3B - MBS8211222 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATAD3B(NM_031921.4) - SHG078973 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATAD3B siRNA - orb273709 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATAD3B shRNA Plasmid (Human) - CHJ3208 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATAD3B miRNA 3'UTR clone - MiUTR1H-00652 from Creative biogene

Species Reactivities Human
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