Gene Symbol |
ARPC1A
|
Entrez Gene |
10552
|
Alt Symbol |
Arc40, HEL-68, SOP2Hs, SOP2L
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
actin related protein 2/3 complex, subunit 1A, 41kDa
|
Other Description |
SOP2-like protein|actin binding protein (Schizosaccharomyces pombe sop2-like)|actin-related protein 2/3 complex subunit 1A|epididymis luminal protein 68
|
Swissprots |
Q8IXQ0 Q86WU5 B4DLQ7 Q7Z5U8 Q92747 D6W5S1 A4D276
|
Accessions |
AAS00381 EAL23883 EAW76681 EAW76682 EAW76683 Q92747 AB209059 BAD92296 AK223015 BAD96735 BC006445 BC039594 AAH39594 BC047889 AAH47889 BC054027 AAH54027 BM924483 DA089818 EU668326 ACF94479 EU832112 ACE87462 EU832206 ACE86776 JF432387 ADZ15604 Y08999 CAA70203 NM_001190996 NP_001177925 NM_006409 NP_006400
|
Function |
Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
|
Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000305}.
|
Top Pathways |
Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton
|