Gene Symbol | ARPC1A |
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Entrez Gene | 10552 |
Alt Symbol | Arc40, HEL-68, SOP2Hs, SOP2L |
Species | Human |
Gene Type | protein-coding |
Description | actin related protein 2/3 complex, subunit 1A, 41kDa |
Other Description | SOP2-like protein|actin binding protein (Schizosaccharomyces pombe sop2-like)|actin-related protein 2/3 complex subunit 1A|epididymis luminal protein 68 |
Swissprots | Q8IXQ0 Q86WU5 B4DLQ7 Q7Z5U8 Q92747 D6W5S1 A4D276 |
Accessions | AAS00381 EAL23883 EAW76681 EAW76682 EAW76683 Q92747 AB209059 BAD92296 AK223015 BAD96735 BC006445 BC039594 AAH39594 BC047889 AAH47889 BC054027 AAH54027 BM924483 DA089818 EU668326 ACF94479 EU832112 ACE87462 EU832206 ACE86776 JF432387 ADZ15604 Y08999 CAA70203 NM_001190996 NP_001177925 NM_006409 NP_006400 |
Function | Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000305}. |
Top Pathways | Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton |
p41-ARCa CRISPR/Cas9 KO Plasmid (h) - sc-417442 from Santa Cruz Biotechnology
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p41-ARCa HDR Plasmid (h) - sc-417442-HDR from Santa Cruz Biotechnology
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p41-ARCa Double Nickase Plasmid (h) - sc-417442-NIC from Santa Cruz Biotechnology
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p41-ARCa Double Nickase Plasmid (h2) - sc-417442-NIC-2 from Santa Cruz Biotechnology
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p41-ARCa CRISPR Activation Plasmid (h) - sc-417442-ACT from Santa Cruz Biotechnology
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p41-ARCa CRISPR Activation Plasmid (h2) - sc-417442-ACT-2 from Santa Cruz Biotechnology
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p41-ARCa Lentiviral Activation Particles (h) - sc-417442-LAC from Santa Cruz Biotechnology
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p41-ARCa Lentiviral Activation Particles (h2) - sc-417442-LAC-2 from Santa Cruz Biotechnology
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p41-ARCa siRNA (h) - sc-89614 from Santa Cruz Biotechnology
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p41-ARCa shRNA Plasmid (h) - sc-89614-SH from Santa Cruz Biotechnology
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p41-ARCa shRNA (h) Lentiviral Particles - sc-89614-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU105471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3525 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3525 from Sigma-Aldrich
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ARPC1A siRNA (Human) - CRH7173 from Cohesion Biosciences
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ARPC1A - MBS8208408 from MyBioSource
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shRNA set against Human ARPC1A (NM_006409.3) - SHH240606 from Creative biogene
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Human ARPC1A siRNA - orb267675 from Biorbyt
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ARPC1A shRNA Plasmid (Human) - CHH7173 from Cohesion Biosciences
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ARPC1A miRNA 3'UTR clone - MiUTR3H-06654 from Creative biogene
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