Gene Symbol | ARPC1A |
---|---|
Entrez Gene | 10552 |
Alt Symbol | Arc40, HEL-68, SOP2Hs, SOP2L |
Species | Human |
Gene Type | protein-coding |
Description | actin related protein 2/3 complex, subunit 1A, 41kDa |
Other Description | SOP2-like protein|actin binding protein (Schizosaccharomyces pombe sop2-like)|actin-related protein 2/3 complex subunit 1A|epididymis luminal protein 68 |
Swissprots | Q8IXQ0 Q86WU5 B4DLQ7 Q7Z5U8 Q92747 D6W5S1 A4D276 |
Accessions | AAS00381 EAL23883 EAW76681 EAW76682 EAW76683 Q92747 AB209059 BAD92296 AK223015 BAD96735 BC006445 BC039594 AAH39594 BC047889 AAH47889 BC054027 AAH54027 BM924483 DA089818 EU668326 ACF94479 EU832112 ACE87462 EU832206 ACE86776 JF432387 ADZ15604 Y08999 CAA70203 NM_001190996 NP_001177925 NM_006409 NP_006400 |
Function | Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000305}. |
Top Pathways | Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton |