NPW

Gene Symbol NPW
Entrez Gene 283869
Alt Symbol L8, L8C, PPL8, PPNPW
Species Human
Gene Type protein-coding
Description neuropeptide W
Other Description hPPL8|prepro-neuropeptide W|preproprotein L8
Swissprots Q8N729
Accessions Q8N729 AB084276 BAC07172 AL365519 AL365521 BC150534 AAI50535 BC160149 AAI60149 BC171886 BM985063 CK817957 NM_001099456 NP_001092926
Function Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity). NPW23 activates GPR7 and GPR8 more efficiently than NPW30. {ECO:0000250}.
Subcellular Location Secreted.
Tissue Specificity Detected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma.

Human NPW ORF clone (NM_001099456.2) - CDCL139573 from Creative biogene

Species Human

Human NPW cDNA Clone(NM_001099456.2) - CDFH012748 from Creative biogene

Species Human
Search more