Gene Symbol | ABCA1 |
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Entrez Gene | 19 |
Alt Symbol | ABC-1, ABC1, CERP, HDLDT1, TGD |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 1 |
Other Description | ATP-binding cassette sub-family A member 1|ATP-binding cassette transporter A1|cholesterol efflux regulatory protein|membrane-bound |
Swissprots | Q96S56 O95477 Q9NQV4 Q9UN06 Q9UN08 Q9UN07 Q5VX33 Q96T85 Q9UN09 |
Accessions | AAD49851 AAD49852 AAD49853 AAD49854 AAF86276 AAK43526 CAC21428 CCQ43324 EAW58992 EAW58993 EAW58994 O95477 AB037924 BAB07875 AB055982 BAB63210 AB208839 BAD92076 AB445477 BAH10664 AF165281 AAD49849 AF258627 AAF69513 AF285167 AAF98175 AJ012376 CAA10005 AK024328 AK027864 BC034824 BC146856 AAI46857 BU753834 BX955241 XM_005251773 XP_005251830 XM_005251776 XP_005251833 XM_011518339 XP_011516641 XM_011518340 XP_011516642 XM_011518341 XP_011516643 XM_011518342 XP_011516644 XM_011518343 XP_011516645 XM_011518344 XP_011516646 NM_005502 NP_005493 |
Function | cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport. |
Subcellular Location | Membrane {ECO:0000269|PubMed:19258317, ECO:0000269|PubMed:19556522}; Multi-pass membrane protein {ECO:0000269|PubMed:19258317, ECO:0000269|PubMed:19556522}. |
Tissue Specificity | Widely expressed, but most abundant in macrophages. |
Top Pathways | ABC transporters, Fat digestion and absorption |
ABC1 (N-15) - sc-5491 from Santa Cruz Biotechnology
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ABC1 (H-220) - sc-20794 from Santa Cruz Biotechnology
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ABC1 (Y-15) - sc-5490 from Santa Cruz Biotechnology
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ABC1 (T-15) - sc-5492 from Santa Cruz Biotechnology
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ABC1 (AC10) - sc-53482 from Santa Cruz Biotechnology
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ABC1 (AB.H10) - sc-58219 from Santa Cruz Biotechnology
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ABC1 (A00121.01) - sc-81779 from Santa Cruz Biotechnology
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Anti-ABCA1 (phospho S2054) antibody [EPR2485] - ab125064 from Abcam
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Anti-ABCA1 antibody - ab7360 from Abcam
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Anti-ABCA1 antibody (Biotin) - ab81950 from Abcam
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Anti-ABCA1 antibody [HJ1] - ab66217 from Abcam
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Anti-ABCA1 antibody [HJ1] (FITC) - ab150275 from Abcam
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Anti-ABCA1 antibody [HJ1] - BSA and Azide free - ab175344 from Abcam
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Anti-ABCA1 Antibody (N-Terminus) - LS-C63367 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (N-Terminus) - LS-C63373 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (N-Terminus) - LS-C63378 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (HRP) - LS-C83839 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (PE) - LS-C124841 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (aa1800-2260) - LS-C122568 from LifeSpan Bioscience
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Anti-ABCA1 Antibody - LS-C126509 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (FITC) - LS-C126510 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (aa200-250, clone 3A1.891.3) - LS-C2751 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (clone 5A1-1422.11) - LS-C2752 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (aa1800-2260, clone AB.H10) - LS-C136791 from LifeSpan Bioscience
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Anti-ABCA1 Antibody (DY650) - LS-C142144 from LifeSpan Bioscience
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